Background The initiation of atherosclerosis (AS) is attributed to the dysfunction of
endothelial cells (ECs) via the inhibition of g protein-coupled estrogen receptor (GPER). In …

The proliferation and apoptosis of cells in the placenta play a critical role in preeclampsia
(PE) in which estrogen has been implicated via estrogen receptors (ERs). A novel ER, G …

Although female protection from cardiovascular diseases declines with the fall in circulating
sex hormones experienced during menopause, clinical trials in older women fail to …

Stress-induced cardiovascular diseases characterized by inflammation are among the
leading causes of morbidity and mortality in postmenopausal women worldwide. Estradiol …

While classical cannabinoid receptors are known to crucially impact on myocardial infarction
(MI) repair, a function of the cannabinoid-sensitive receptor GPR55 herein is poorly …

G-protein-coupled estrogen receptor-30 (GPR30), also known as G-protein estrogen
receptor-1 (GPER1), is a putative extranuclear estrogen receptor whose precise functions in …

Secretion of multifunctional estrogen and its receptor has been widely considered as the
reason for markedly higher frequency of heart disease in men than in women. 17β-Estradiol …

Obesity has become a serious global public health problem, and cardiomyopathy caused by
obesity has recently gained attention. As an important protein involved in glucose and lipid …

The effect of estrogen receptors on diabetes-induced vascular dysfunction is critical, but
ambiguous. Individuals with diabetic vascular disease may require estrogen receptor …

Estrogen deficiency is associated with increased incidence of cardiovascular diseases. But
merely estrogen supplementary treatment can induce many severe complications such as …