Particulate matter inhibits DNA repair and enhances mutagenesis
Exposure to ambient air pollution has been associated with adverse health effects including
lung cancer. A recent epidemiology study has established that each 10μg/m3 elevation in …
lung cancer. A recent epidemiology study has established that each 10μg/m3 elevation in …
Oxidative stress-induced DNA damage by particulate air pollution
L Risom, P Møller, S Loft - Mutation Research/Fundamental and Molecular …, 2005 - Elsevier
Exposure to ambient air particulate matter (PM) is associated with pulmonary and
cardiovascular diseases and cancer. The mechanisms of PM-induced health effects are …
cardiovascular diseases and cancer. The mechanisms of PM-induced health effects are …
Airborne particulate matter induces oxidative damage, DNA adduct formation and alterations in DNA repair pathways
EM Quezada-Maldonado, Y Sánchez-Pérez… - Environmental …, 2021 - Elsevier
Air pollution, which includes particulate matter (PM), is classified in group 1 as a carcinogen
to humans by the International Agency for Research in Cancer. Specifically, PM exposure …
to humans by the International Agency for Research in Cancer. Specifically, PM exposure …
DNA damage response of A549 cells treated with particulate matter (PM10) of urban air pollutants
Y Sánchez-Pérez, YI Chirino, ÁR Osornio-Vargas… - Cancer letters, 2009 - Elsevier
We describe the events triggered by a sub-lethal concentration of airborne particulate matter
(PM10) in A549 cells, which include the formation DNA double-strand breaks, γH2A. X …
(PM10) in A549 cells, which include the formation DNA double-strand breaks, γH2A. X …
Oxidative stress and inflammation generated DNA damage by exposure to air pollution particles
P Møller, PH Danielsen, DG Karottki, K Jantzen… - … research/Reviews in …, 2014 - Elsevier
Generation of oxidatively damaged DNA by particulate matter (PM) is hypothesized to occur
via production of reactive oxygen species (ROS) and inflammation. We investigated this …
via production of reactive oxygen species (ROS) and inflammation. We investigated this …
Linking exposure to environmental pollutants with biological effects
M Sørensen, H Autrup, P Møller, O Hertel… - … Research/Reviews in …, 2003 - Elsevier
Exposure to ambient air pollution has been associated with cancer. Ambient air contains a
complex mixture of toxics, including particulate matter (PM) and benzene. Carcinogenic …
complex mixture of toxics, including particulate matter (PM) and benzene. Carcinogenic …
Air pollution, oxidative damage to DNA, and carcinogenesis
P Møller, JK Folkmann, L Forchhammer, EV Bräuner… - Cancer letters, 2008 - Elsevier
There is growing concern that air pollution exposure increases the risk of lung cancer. The
mechanism of action is related to particle-induced oxidative stress and oxidation of DNA …
mechanism of action is related to particle-induced oxidative stress and oxidation of DNA …
Effect of chemical composition on the induction of DNA damage by urban airborne particulate matter
ME Gutiérrez‐Castillo, DA Roubicek… - Environmental and …, 2006 - Wiley Online Library
Airborne particulate matter (PM) contains a large number of genotoxic substances capable
of endangering human health. In the present study, we have investigated the ability of …
of endangering human health. In the present study, we have investigated the ability of …
Role of DNA repair in particle-and fiber-induced lung injury
A Hartwig - Inhalation toxicology, 2002 - Taylor & Francis
Lung injury after particle exposure is associated with the generation of reactive oxygen
species (ROS), leading to increased levels of oxidative DNA damage. Furthermore, both …
species (ROS), leading to increased levels of oxidative DNA damage. Furthermore, both …
Nanoparticle-driven DNA damage mimics irradiation-related carcinogenesis pathways
RM Mroz, RPF Schins, H Li, LA Jimenez… - European …, 2008 - Eur Respiratory Soc
The epidemiological association between cancer and exposure to ambient air pollution
particles (particles with a 50% cut-off aerodynamic diameter of 10 μm (PM10)) has been …
particles (particles with a 50% cut-off aerodynamic diameter of 10 μm (PM10)) has been …
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