Language is a defining characteristic of the human species, but its foundations remain
mysterious. Heritable disorders offer a gateway into biological underpinnings, as illustrated …

The human capacity to acquire sophisticated language is unmatched in the animal kingdom.
Despite the discontinuity in communicative abilities between humans and other primates …

▪ Abstract A significant number of individuals have unexplained difficulties with acquiring
normal speech and language, despite adequate intelligence and environmental stimulation …

We previously discovered that mutations of the human FOXP2 gene cause a monogenic
communication disorder, primarily characterized by difficulties in learning to make …

Highlights•Rare variants disrupting speech, in genes like FOXP2, give insight into
neurobiology of key human traits.•Neural functions of FOXP2 are being studied in human …

Developmental disorders affecting speech and language are highly heritable, but very little
is currently understood about the neuromolecular mechanisms that underlie these traits …

Rare mutations of the FOXP2 transcription factor gene cause a monogenic syndrome
characterized by impaired speech development and linguistic deficits. Recent genomic …

The integration of language pathologies, genetics, brain imaging, molecular embryology,
and sequential gene expression, by means of DNA/RNA/proteomics, is a remarkable open …

Researchers are beginning to uncover the neurogenetic pathways that underlie our
unparalleled capacity for spoken language. Initial clues come from identification of genetic …

Mutations of the FOXP2 gene cause a severe speech and language disorder, providing a
molecular window into the neurobiology of language. Individuals with FOXP2 mutations …