Understanding language from a genomic perspective
SA Graham, SE Fisher - Annual review of genetics, 2015 - annualreviews.org
Language is a defining characteristic of the human species, but its foundations remain
mysterious. Heritable disorders offer a gateway into biological underpinnings, as illustrated …
mysterious. Heritable disorders offer a gateway into biological underpinnings, as illustrated …
Insights into the genetic foundations of human communication
SA Graham, P Deriziotis, SE Fisher - Neuropsychology Review, 2015 - Springer
The human capacity to acquire sophisticated language is unmatched in the animal kingdom.
Despite the discontinuity in communicative abilities between humans and other primates …
Despite the discontinuity in communicative abilities between humans and other primates …
Deciphering the genetic basis of speech and language disorders
▪ Abstract A significant number of individuals have unexplained difficulties with acquiring
normal speech and language, despite adequate intelligence and environmental stimulation …
normal speech and language, despite adequate intelligence and environmental stimulation …
High-throughput analysis of promoter occupancy reveals direct neural targets of FOXP2, a gene mutated in speech and language disorders
We previously discovered that mutations of the human FOXP2 gene cause a monogenic
communication disorder, primarily characterized by difficulties in learning to make …
communication disorder, primarily characterized by difficulties in learning to make …
[HTML][HTML] Genetic pathways involved in human speech disorders
J Den Hoed, SE Fisher - Current Opinion in Genetics & Development, 2020 - Elsevier
Highlights•Rare variants disrupting speech, in genes like FOXP2, give insight into
neurobiology of key human traits.•Neural functions of FOXP2 are being studied in human …
neurobiology of key human traits.•Neural functions of FOXP2 are being studied in human …
Dissection of molecular mechanisms underlying speech and language disorders
SE Fisher - Applied Psycholinguistics, 2005 - cambridge.org
Developmental disorders affecting speech and language are highly heritable, but very little
is currently understood about the neuromolecular mechanisms that underlie these traits …
is currently understood about the neuromolecular mechanisms that underlie these traits …
FOXP2 as a molecular window into speech and language
Rare mutations of the FOXP2 transcription factor gene cause a monogenic syndrome
characterized by impaired speech development and linguistic deficits. Recent genomic …
characterized by impaired speech development and linguistic deficits. Recent genomic …
Decoding the genetics of speech and language
SA Graham, SE Fisher - Current opinion in neurobiology, 2013 - Elsevier
Researchers are beginning to uncover the neurogenetic pathways that underlie our
unparalleled capacity for spoken language. Initial clues come from identification of genetic …
unparalleled capacity for spoken language. Initial clues come from identification of genetic …
A geneticist's dream, a linguist's nightmare: The case of FOXP2
M Piattelli-Palmarini - Biolinguistic Investigations and the Formal …, 2018 - taylorfrancis.com
The integration of language pathologies, genetics, brain imaging, molecular embryology,
and sequential gene expression, by means of DNA/RNA/proteomics, is a remarkable open …
and sequential gene expression, by means of DNA/RNA/proteomics, is a remarkable open …
Mapping of Human FOXP2 Enhancers Reveals Complex Regulation
Mutations of the FOXP2 gene cause a severe speech and language disorder, providing a
molecular window into the neurobiology of language. Individuals with FOXP2 mutations …
molecular window into the neurobiology of language. Individuals with FOXP2 mutations …