Immunotherapy treatments harnessing the immune system herald a new era of personalized
medicine, offering considerable benefits for cancer patients. Over the past years, tumor …

Within the past decade, the field of immunotherapy has revolutionized the treatment of many
cancers with the development and regulatory approval of various immune-checkpoint …

The recent success of cancer immunotherapies has highlighted the benefit of harnessing the
immune system for cancer treatment. Vaccines have a long history of promoting immunity to …

Introduction The discovery of neoantigens as mutated proteins specifically expressed in
tumor cells but not in normal cells has led to improved cancer vaccines. Targeting …

Recently, increasing data show that immunotherapy could be a powerful weapon against
cancers. Comparing to the traditional surgery, chemotherapy or radiotherapy …

Alternatives to conventional cancer treatments are highly sought after for high-risk
malignancies that have a poor response to established treatment modalities. With research …

Neoantigen vaccines are based on epitopes of antigenic parts of mutant proteins expressed
in cancer cells. These highly immunogenic antigens may trigger the immune system to …

Cancer immunotherapy has achieved multiple clinical benefits and has become an
indispensable component of cancer treatment. Targeting tumor-specific antigens, also …

Cancer immunotherapies are treatments that use drugs or cells to activate patients' own
immune systems against cancer cells. Among them, cancer vaccines have recently been …

Somatic mutations in cancer cells can generate tumour-specific neoepitopes, which are
recognized by autologous T cells in the host. As neoepitopes are not subject to central …