Botulinum neurotoxins (BoNTs) are potent inhibitors of synaptic vesicle fusion and
transmitter release. The natural target of BoNTs is the peripheral neuromuscular junction …

In recent years, numerous studies have highlighted the significant use of botulinum
neurotoxins (BoNTs) in the human therapy of various motor and autonomic disorders. The …

For more than three decades, Botulinum neurotoxin (BoNT) has been used to treat a variety
of clinical conditions such as spastic or dystonic disorders by inducing a temporary paralysis …

Botulinum neurotoxins (BoNTs) cause flaccid paralysis by interfering with vesicle fusion and
neurotransmitter release in the neuronal cells. BoNTs are the most widely used therapeutic …

Botulinum neurotoxin type A (BoNT/A) is a metalloprotease that produces a sustained yet
transitory blockade of transmitter release from peripheral nerve terminals. Local delivery of …

The study of botulinum neurotoxins (BoNT) is rapidly progressing in many aspects. Novel
BoNTs are being discovered owing to next generation sequencing, but their biologic and …

Botulinum neurotoxins (BoNTs) are highly potent toxins responsible for a severe disease,
called botulism. They are also efficient therapeutic tools with an increasing number of …

The use of botulinum neurotoxins (BoNTs) for therapeutic purposes in neuromuscular
disorders and peripheral hypercholinergic conditions as well as in aesthetic medicine is …

Botulinum neurotoxin Type A (BoNT/A) is an effective treatment for several movement
disorders, including spasticity and dystonia. BoNT/A acts by cleaving synaptosomal …

This review presents a brief account of the most significant biological effects and clinical
applications of botulinum neurotoxins, in a way comprehensive even for casual readers who …