Abstract At a previous International Symposium on Plasma Protein Metabolism 1 we
presented evidence that patients with advanced carcinomas of the lung, pancreas and liver …

To provide more information on the pathways of fibrinogen catabolism in generalized
cancer, the effect of heparin on fibrinopeptide A (fpA) and on 125I-fibrinogen kinetics was …

FPA level, fibrinogen turnover rate, and fibrinolytic activity were studied on 18 patients with
malignant disease. It was found that the FPA levels were significantly elevated and were …

In 124 patients with various types of malignancy, fpA and ΔfpA were measured. In 35 of
these patients the effect of heparin injection on fpA and ΔfpA was studied. All patients were …

Only limited data are available regarding the distribution and elimination of fibrinopeptides,
which are cleaved from fibrinogen during the coagulation and fibrinolytic process. Recently …

Fibrinogen is a thrombin-coagulable glycoprotein occurring in the blood of vertebrates. The
primary structure of the α, β, and γ polypeptide chains of human fibrinogen is known from …

Highly purified, fibrinogen–fibrin related antigen (FR‐antigen) was isolated with good
recovery from 1.0–2.0 ml of human plasma, by immunoaffinity chromatography with antibody …

Although the site and manner of normal catabolism of most of the fibrinogen pool is
uncertain, certain pathways have been defined for various fibrinogen derivatives. Several …

The metabolism of human fibrinogen, labelled with radioactive iodine, was studied in 35
healthy subjects over a 5 yr period using eight fibrinogen preparations in 23 labelling …

Mean urinary excretion of fibrinopeptide-A (FPA) in 51 normal individuals ranging in age
from 7 to 92 yr was 1.67±. 1 (SE) μg/24 hr with no significant differences related to age or …