Twenty-two years of phase III trials for patients with advanced non–small-cell lung cancer: Sobering results

OS Breathnach, B Freidlin, B Conley… - Journal of Clinical …, 2001 - ascopubs.org
PURPOSE: To determine the changes in clinical trials and outcomes of patients with
advanced-stage non–small-cell lung cancer (NSCLC) treated on phase III randomized trials …

Clinical practice guidelines for the treatment of unresectable non-small-cell lung cancer. Adopted on May 16, 1997 by the American Society of Clinical Oncology.

American Society of Clinical Oncology - Journal of Clinical Oncology, 1997 - cir.nii.ac.jp
抄録< jats: sec>< jats: title> PURPOSE</jats: title>< jats: p> The primary objective was to
determine clinical practice guidelines for the diagnostic evaluation, treatment, and follow-up …

[HTML][HTML] American Society of Clinical Oncology clinical practice guideline update on chemotherapy for stage IV non–small-cell lung cancer

CG Azzoli, S Baker Jr, S Temin, W Pao… - Journal of clinical …, 2009 - ncbi.nlm.nih.gov
The purpose of this article is to provide updated recommendations for the treatment of
patients with stage IV non–small-cell lung cancer. A literature search identified relevant …

Chemotherapy for advanced non-small-cell lung cancer: how much benefit is enough?

R Grilli, AD Oxman, JA Julian - Journal of clinical oncology, 1993 - ascopubs.org
PURPOSE To estimate the impact of chemotherapy on survival of patients with advanced
non-small-cell lung cancer (NSCLC). METHODS Randomized controlled trials (RCTs) …

Chemotherapy can prolong survival in patients with advanced non-small-cell lung cancer--report of a Canadian multicenter randomized trial.

E Rapp, JL Pater, A Willan, Y Cormier… - Journal of Clinical …, 1988 - ascopubs.org
The survival benefit of combination chemotherapy to patients with advanced non-small-cell
carcinoma of the lung (NSCLC) is controversial. To study this question, the National Cancer …

Considerations for second-line therapy of non-small cell lung cancer

TE Stinchcombe, MA Socinski - The oncologist, 2008 - academic.oup.com
For patients with advanced non-small cell lung cancer and a good functional status,
platinum-based first-line chemotherapy improves quality of life, reduces disease-related …

Improved survival in stage III non-small-cell lung cancer: seven-year follow-up of cancer and leukemia group B (CALGB) 8433 trial

RO Dillman, J Herndon, SL Seagren… - JNCI: Journal of the …, 1996 - academic.oup.com
Background: For many years, high-dose radiation therapy was the standard treatment for
patients with locally or regionally advanced non-small-cell lung cancer (NSCLC), despite a 5 …

Phase III trial comparing a defined duration of therapy versus continuous therapy followed by second-line therapy in advanced-stage IIIB/IV non–small-cell lung cancer

MA Socinski, MJ Schell, A Peterman, K Bakri… - Journal of Clinical …, 2002 - ascopubs.org
PURPOSE: To compare four cycles of therapy versus continuous therapy to determine the
optimal duration of chemotherapy in advanced non–small-cell lung cancer (NSCLC) …

Strategies for prolonged therapy in patients with advanced non-small-cell lung cancer.

P Fidias, S Novello - Journal of Clinical Oncology, 2010 - iris.unito.it
PURPOSE: A key challenge in the treatment of advanced non-small-cell lung cancer
(NSCLC) is improving outcomes for patients who have achieved at least stable disease after …

[HTML][HTML] Duration of chemotherapy for advanced non-small-cell lung cancer: a systematic review and meta-analysis of randomized trials

YY Soon, MR Stockler, LM Askie… - Database of Abstracts of …, 2009 - ncbi.nlm.nih.gov
This well-conducted review concluded that extension of chemotherapy, particularly with a
third-generation regimen, substantially improved progression-free survival and had a lesser …