[HTML][HTML] Metabolic regulation of epithelial to mesenchymal transition: implications for endocrine cancer

D Bhattacharya, A Scimè - Frontiers in Endocrinology, 2019 - frontiersin.org
The last few decades have witnessed an outstanding advancement in our understanding of
the hallmarks of endocrine cancers. This includes the epithelial to mesenchymal transition …

[HTML][HTML] Metabolic reprogramming and epithelial-mesenchymal plasticity: opportunities and challenges for cancer therapy

NY Sun, MH Yang - Frontiers in oncology, 2020 - frontiersin.org
Metabolic reprogramming and epithelial-mesenchymal plasticity are both hallmarks of the
adaptation of cancer cells for tumor growth and progression. For metabolic changes, cancer …

[HTML][HTML] TGFβ-induced metabolic reprogramming during epithelial-to-mesenchymal transition in cancer

W Hua, P Ten Dijke, S Kostidis, M Giera… - Cellular and Molecular …, 2020 - Springer
Metastasis is the most frequent cause of death in cancer patients. Epithelial-to-mesenchymal
transition (EMT) is the process in which cells lose epithelial integrity and become motile, a …

[HTML][HTML] Interplay between metabolism reprogramming and epithelial-to-mesenchymal transition in cancer stem cells

Y Daniel, E Lelou, C Aninat, A Corlu, F Cabillic - Cancers, 2021 - mdpi.com
Simple Summary Tumor cells display important plasticity potential. Notably, tumor cells have
the ability to change toward immature cells called cancer stem cells under the influence of …

[HTML][HTML] Epithelial-mesenchymal transition and metabolic switching in cancer: lessons from somatic cell reprogramming

X Lai, Q Li, F Wu, J Lin, J Chen, H Zheng… - Frontiers in cell and …, 2020 - frontiersin.org
Epithelial-mesenchymal transition (EMT) and its critical roles during cancer progression
have long been recognized and extensively reviewed. Recent studies on the generation of …

[HTML][HTML] Role of metabolic reprogramming in epithelial–mesenchymal transition (EMT)

H Kang, H Kim, S Lee, HS Youn, BH Youn - International Journal of …, 2019 - mdpi.com
Activation of epithelial–mesenchymal transition (EMT) is thought to be an essential step for
cancer metastasis. Tumor cells undergo EMT in response to a diverse range of extra-and …

[HTML][HTML] Targeting the metabolic reprogramming that controls epithelial-to-mesenchymal transition in aggressive tumors

A Morandi, ML Taddei, P Chiarugi, E Giannoni - Frontiers in oncology, 2017 - frontiersin.org
The epithelial-to-mesenchymal transition (EMT) process allows the trans-differentiation of a
cell with epithelial features into a cell with mesenchymal characteristics. This process has …

[HTML][HTML] Biological role of metabolic reprogramming of cancer cells during epithelial‑mesenchymal transition

M Li, X Bu, B Cai, P Liang, K Li, X Qu… - Oncology …, 2019 - spandidos-publications.com
Epithelial‑mesenchymal transition (EMT) is required for the distant metastasis of tumors. The
degree of tumor malignancy increases as EMT progresses. Notably, the biology of tumor …

Epithelial–mesenchymal transition in human cancer: comprehensive reprogramming of metabolism, epigenetics, and differentiation

L Li, W Li - Pharmacology & therapeutics, 2015 - Elsevier
The epithelial–mesenchymal transition (EMT) is a developmental process that is important
for embryogenesis, wound healing, organ fibrosis, and cancer metastasis. Cancer …

Metabolic reprogramming and epithelial‐to‐mesenchymal transition in cancer

M Sciacovelli, C Frezza - The FEBS journal, 2017 - Wiley Online Library
Several lines of evidence indicate that during transformation epithelial cancer cells can
acquire mesenchymal features via a process called epithelial‐to‐mesenchymal transition …