[HTML][HTML] Role of Pex19p in the targeting of PMP70 to peroxisome

Y Kashiwayama, K Asahina, H Shibata, M Morita… - … Et Biophysica Acta (BBA …, 2005 - Elsevier
Pex19p is a protein required for the peroxisomal membrane synthesis. The 70-kDa
peroxisomal membrane protein (PMP70) is synthesized on free cytosolic ribosomes and …

[HTML][HTML] Hydrophobic regions adjacent to transmembrane domains 1 and 5 are important for the targeting of the 70-kDa peroxisomal membrane protein

Y Kashiwayama, K Asahina, M Morita… - Journal of biological …, 2007 - ASBMB
The 70-kDa peroxisomal membrane protein (PMP70) is a major component of peroxisomal
membranes. Human PMP70 consists of 659 amino acid residues and has six putative …

[HTML][HTML] Two different targeting signals direct human peroxisomal membrane protein 22 to peroxisomes

U Brosius, T Dehmel, J Gärtner - Journal of Biological Chemistry, 2002 - ASBMB
The 22-kDa peroxisomal membrane protein (PMP22) is a major component of peroxisomal
membranes in mammals. Although its precise role in peroxisome function is poorly …

Targeting elements in the amino-terminal part direct the human 70-kDa peroxisomal integral membrane protein (PMP70) to peroxisomes

M Biermanns, J Gärtner - Biochemical and Biophysical Research …, 2001 - Elsevier
Peroxisomes are multipurpose organelles present in nearly all eukaryotic cells. All
peroxisomale matrix and membrane proteins are synthesized in the cytoplasm. While a clear …

Multiple organelle-targeting signals in the N-terminal portion of peroxisomal membrane protein PMP70

S Iwashita, M Tsuchida, M Tsukuda… - The journal of …, 2010 - academic.oup.com
Most membrane proteins are recognized by a signal recognition particle and are
cotranslationally targeted to the endoplasmic reticulum (ER) membrane, whereas almost all …

[HTML][HTML] Domain architecture and activity of human Pex19p, a chaperone-like protein for intracellular trafficking of peroxisomal membrane proteins

H Shibata, Y Kashiwayama, T Imanaka… - Journal of Biological …, 2004 - ASBMB
Pex19p is a peroxin involved in peroxisomal membrane biogenesis and probably functions
as a chaperone and/or soluble receptor specific for cargo peroxisomal membrane proteins …

Redox-sensitive homodimerization of Pex11p: a proposed mechanism to regulate peroxisomal division.

PA Marshall, JM Dyer, ME Quick… - The Journal of cell …, 1996 - rupress.org
Pex11p (formerly Pmp27) has been implicated in peroxisomal proliferation (Erdmann, R.,
and G. Blobel. 1995. J. Cell Biol. 128; 509-523; Marshall, PA, YI Krimkevich, RH Lark, JM …

PEX19 binds multiple peroxisomal membrane proteins, is predominantly cytoplasmic, and is required for peroxisome membrane synthesis

KA Sacksteder, JM Jones, ST South, X Li, Y Liu… - The Journal of cell …, 2000 - rupress.org
Peroxisomes are components of virtually all eukaryotic cells. While much is known about
peroxisomal matrix protein import, our understanding of how peroxisomal membrane …

[HTML][HTML] Pex19p-dependent targeting of Pex17p, a peripheral component of the peroxisomal protein import machinery

W Girzalsky, LS Hoffmann, A Schemenewitz… - Journal of Biological …, 2006 - ASBMB
Pex19p is required for the topogenesis of peroxisomal membrane proteins (PMPs). Here we
have demonstrated that Pex19p is also required for the peroxisomal targeting and stability of …

[HTML][HTML] Discrete targeting signals direct Pmp47 to oleate-induced peroxisomes in Saccharomyces cerevisiae

X Wang, MJ Unruh, JM Goodman - Journal of Biological Chemistry, 2001 - ASBMB
Pmp47 is a peroxisomal membrane protein consisting of six transmembrane domains
(TMDs). We previously showed that the second matrix loop containing a basic cluster of …