Indications for the measurement of plasma digoxin concentrations

JK Aronson - Drugs, 1983 - Springer
The criteria which a drug must fulfil before it can be said that it may be worthwhile making
regular plasma concentration measurements of that drug in monitoring therapy are …

Interpretation of the serum digoxin concentration

M Weintraub - Clinical Pharmacokinetics, 1977 - Springer
Significant problems exist in the interpretation of serum digoxin concentration data. Failure
to distinguish between results that do not require precise clinical correlation (proof of …

Plasma digoxin concentration--its relation to digoxin dosage and clinical effects in patients with atrial fibrillation.

A Redfors - British Heart Journal, 1972 - ncbi.nlm.nih.gov
With a modified, precise 86Rbmethodplasma digoxin concentration was estimated
inpatients with atrialfibrillation. They received successively increasing digoxin dosesuntil …

Inefficacy of “therapeutic” serum levels of digoxin in controlling the ventricular rate in atrial fibrillation

S Goldman, P Probst, A Selzer, K Cohn - The American journal of …, 1975 - Elsevier
Although therapeutic and toxic serum concentrations of digoxin have been established,
there is sparse information permitting correlation of drug level with clinical effect. This study …

Significance of non-steady-state serum digoxin concentrations

LCFM Walsh, J Sode - American Journal of Clinical Pathology, 1975 - academic.oup.com
Abstract Walsh, FM, and Sode, Jonas: Significance of non-steady-state serum digoxin
concentrations. Am J Clin Pathol 63: 446–450, 1975. In order better to define the optimal …

A concurrent audit of high digoxin plasma levels

AA Piergies, EM Worwag… - Clinical Pharmacology & …, 1994 - Wiley Online Library
A concurrent audit was made of 92 patients with plasma or serum digoxin levels of 3.0 ng/ml
or more. Evidence of digoxin toxicity was present in 44 of these patients, and premature …

Monitoring digoxin therapy: the use of plasma digoxin concentration measurements in the diagnosis of digoxin toxicity

JK Aronson, DG Grahame-Smith… - QJM: An International …, 1978 - academic.oup.com
The usefulness of measuring plasma digoxin concentrations in the diagnosis of digoxin
toxicity has been assessed in 83 in-patients. The mean plasma digoxin concentration in …

An audit of requests for therapeutic drug monitoring of digoxin: problems and pitfalls

HW Clague, Y Twum-Barima… - Therapeutic drug …, 1983 - journals.lww.com
The use of serum digoxin measurements in a teaching hospital was audited. The reason for
test requisition, the timing of blood samples, the recognition of results, and the action taken …

Correlation between electrocardiographic changes, serum digoxin, and total body digoxin content

P Joubert, B Kroening, M Weintraub… - Clinical …, 1976 - Wiley Online Library
Serial electrocardiograms and serum digoxin levels were obtained in four healthy volunteers
receiving daily doses of digoxin, 0.25 mg for the first two weeks and 0.5 mg for two more …

Therapeutic drug monitoring of digoxin: help or hindrance?

RJ Dobbs, PW Nicholson, MJ Denham… - European journal of …, 1986 - Springer
A major role of therapeutic drug monitoring services is to advise on the dose of a drug which
would be required to bring the concentration in the blood to within specific 'therapeutic'limits …