Serum digoxin levels were determined in 33 outpatients of a general practice in the
countryside, on three occasions at intervals of 8 weeks. All the patients were on long term …

Radioimmunoassay of digoxin and measurements of ventricular rate at rest and exercise
were performed four times daily during maintenance therapy and following discontinuation …

Nine healthy male volunteers received single 0.5, 1.0, and 1.5 mg. doses of intravenous
digoxin in a randomized three-way crossover study. Multiple venous blood samples were …

After obtaining samples at open heart surgery, serum and right atrial digoxin concentrations
were measured in 25 children by a nonspecific, direct radioimmunoassay method (NS) and …

The quality and comparability of five RIA's available on the German market for determination
of digoxin are tested in this paper. All RIA's produced varying results in the determination of …

The digitalis drugs are plant-derived cardenolide compounds used medicinally for several
hundred years. These drugs elicit inotropic and chronotropic effects on the heart, but they …

Butler and Chen'first reported on the preparation of digoxin-specific antibodies. Later, Smith
and associates2s3 characterized the antibodies2 and developed a radioimmunoassay for …

The effects of digoxin on electrophysiologic properties were evaluated in isolated perfused
cardiac tissue. In canine Purkinje fiber (PF)-ventricular muscle (VM) preparations, control …

The digoxin-quinidine interaction was studied in nine healthy human subjects aged 26 to 31
years. A single oral dose (400 mg) of quinidine sulfate administered to subjects taking …

Abstract 1 The tendency of a given oral dose of digoxin to induce cardiac dysrhythmia was
determined indirectly at various times after its administration to eight conscious dogs by …