Biodistribution, migration and homing of systemically applied mesenchymal stem/stromal cells

J Leibacher, R Henschler - Stem cell research & therapy, 2016 - Springer
Mesenchymal stem/stromal cells (MSCs) are increasingly used as an intravenously applied
cellular therapeutic. They were found to be potent in situations such as tissue repair or …

Mesenchymal stromal cells promote tumor growth through the enhancement of neovascularization

K Suzuki, R Sun, M Origuchi, M Kanehira… - Molecular …, 2011 - Springer
Mesenchymal stromal cells (MSCs), also called mesenchymal stem cells, migrate and
function as stromal cells in tumor tissues. The effects of MSCs on tumor growth are …

Therapeutic applications of mesenchymal stromal cells: paracrine effects and potential improvements

J Doorn, G Moll, K Le Blanc… - … Engineering Part B …, 2012 - liebertpub.com
Among the various types of cell-to-cell signaling, paracrine signaling comprises those
signals that are transmitted over short distances between different cell types. In the human …

“Stemness” does not explain the repair of many tissues by mesenchymal stem/multipotent stromal cells (MSCs)

DJ Prockop - Clinical Pharmacology & Therapeutics, 2007 - Wiley Online Library
There has recently been an explosion of interest in adult stem/progenitor cells that have the
potential to repair tissues, with over 3,000 citations to publications (PubMed) and numerous …

The (in) auspicious role of mesenchymal stromal cells in cancer: be it friend or foe

S Kidd, E Spaeth, A Klopp, M Andreeff, B Hall… - …, 2008 - Taylor & Francis
Recent progress in the research of mesenchymal stromal cells/multipotent stromal cells
(MSC) has revealed numerous beneficial innate characteristics, suggesting potential value …

Heterogeneity of in vitro expanded mesenchymal stromal cells and strategies to improve their therapeutic actions

L Olmedo-Moreno, Y Aguilera, C Baliña-Sánchez… - Pharmaceutics, 2022 - mdpi.com
Beneficial properties of mesenchymal stromal cells (MSCs) have prompted their use in
preclinical and clinical research. Accumulating evidence has been provided for the …

Vascularization mediated by mesenchymal stem cells from bone marrow and adipose tissue: a comparison

K Pill, S Hofmann, H Redl, W Holnthoner - Cell regeneration, 2015 - Springer
Tissue-engineered constructs are promising to overcome shortage of organ donors and to
reconstruct at least parts of injured or diseased tissues or organs. However, oxygen and …

Mesenchymal stem cell perspective: cell biology to clinical progress

MF Pittenger, DE Discher, BM Péault… - NPJ Regenerative …, 2019 - nature.com
The terms MSC and MSCs have become the preferred acronym to describe a cell and a cell
population of multipotential stem/progenitor cells commonly referred to as mesenchymal …

Heterogeneity of proangiogenic features in mesenchymal stem cells derived from bone marrow, adipose tissue, umbilical cord, and placenta

WJ Du, Y Chi, ZX Yang, ZJ Li, JJ Cui, BQ Song… - Stem Cell Research & …, 2016 - Springer
Abstract Background Mesenchymal stem cells (MSCs) have been widely proven effective for
therapeutic angiogenesis in ischemia animal models as well as clinical vascular diseases …

Mesenchymal stem cells: roles and relationships in vascularization

AJ Melchiorri, BNB Nguyen, JP Fisher - Tissue Engineering Part B …, 2014 - liebertpub.com
One of the primary challenges in translating tissue engineering to clinical applicability is
adequate, functional vascularization of tissue constructs. Vascularization is necessary for the …