Migraine is a common and complex neurologic disorder that affects approximately 15–18%
of the general population. Although the cause of migraine is unknown, some genetic studies …

In the last two decades, migraine research has greatly advanced our current knowledge of
the genetic contributions and the pathophysiology of this common and debilitating disorder …

Understanding the molecular mechanisms that precede and give rise to a migraine attack is
key to developing new therapeutic strategies. Advances towards this goal have recently …

Migraine is a disabling episodic brain disorder with an increased familial relative risk, an
increased concordance in monozygotic twins, and an estimated heritability of approximately …

Significant progress in molecular genetics has advanced our understanding of the genetic
basis of migraine. The fundamentals of molecular genetics, and the recent advances in the …

Background Migraine is a complex neurovascular disorder with a strong genetic component.
There are rare monogenic forms of migraine, as well as more common polygenic forms; …

Background Migraine is considered a multifactorial genetic disorder. Different platforms and
methods are used to unravel the genetic basis of migraine. Initially, linkage analysis in …

Migraine is a common neurological disorder with a strong genetic basis. However, the
complex nature of the disorder has meant that few genes or susceptibility loci have been …

Genetic factors importantly contribute to migraine. However, unlike for rare monogenic forms
of migraine, approaches to identify genes for common forms of migraine have been of …

Migraine is a disabling neurological disorder burdening patients globally. Through the
increasing development of preclinical and clinical experimental migraine models, advancing …