[PDF][PDF] Non-Invasive Methods: Investigation of Airways Diseases by MRI in Rats
N Beckmann, S Zurbruegg, FX Blé - Presenting a special issue of …, 2007 - researchgate.net
Current techniques to evaluate the efficacy of potential treatments for airways diseases in
small animal models are generally invasive and terminal. In this contribution we illustrate the …
small animal models are generally invasive and terminal. In this contribution we illustrate the …
Lung MRI for experimental drug research
N Beckmann, C Cannet, H Karmouty-Quintana… - European journal of …, 2007 - Elsevier
Current techniques to evaluate the efficacy of potential treatments for airways diseases in
preclinical models are generally invasive and terminal. In the past few years, the flexibility of …
preclinical models are generally invasive and terminal. In the past few years, the flexibility of …
Techniques: magnetic resonance imaging of the lung provides potential for non-invasive preclinical evaluation of drugs
N Beckmann, B Tigani, L Mazzoni, JR Fozard - Trends in pharmacological …, 2003 - cell.com
Over the past several years, magnetic resonance imaging (MRI) has become an established
tool in the drug discovery and development process. The main advantages of MRI are its …
tool in the drug discovery and development process. The main advantages of MRI are its …
Longitudinal characterization of a model of chronic allergic lung inflammation in mice using imaging, functional and immunological methods
K Changani, C Pereira, S Young, R Shaw… - Clinical …, 2013 - portlandpress.com
The present study investigated the role that imaging could have for assessing lung
inflammation in a mouse model of HDM (house dust mite)-provoked allergic inflammation …
inflammation in a mouse model of HDM (house dust mite)-provoked allergic inflammation …
Pulmonary edema induced by allergen challenge in the rat: noninvasive assessment by magnetic resonance imaging
N Beckmann, B Tigani, D Ekatodramis… - … in Medicine: An …, 2001 - Wiley Online Library
The course of pulmonary edema formation after an intratracheal (it) instillation of ovalbumin
was followed noninvasively by magnetic resonance imaging (MRI) in actively sensitized …
was followed noninvasively by magnetic resonance imaging (MRI) in actively sensitized …
Lung inflammation and vascular remodeling after repeated allergen challenge detected noninvasively by MRI
B Tigani, C Cannet… - … of Physiology-Lung …, 2007 - journals.physiology.org
Magnetic resonance imaging (MRI) has been used previously to follow noninvasively
inflammatory processes in rat acute models of lung inflammation. Here the technique was …
inflammatory processes in rat acute models of lung inflammation. Here the technique was …
Ultrashort‐TE MRI longitudinal study and characterization of a chronic model of asthma in mice: inflammation and bronchial remodeling assessment
A Bianchi, A Ozier, O Ousova, G Raffard… - NMR in …, 2013 - Wiley Online Library
Asthma is a chronic disease characterized by bronchial hyperresponsiveness (BHR),
bronchial inflammation and remodeling. The great improvements in 1H MRI ultrashort‐TE …
bronchial inflammation and remodeling. The great improvements in 1H MRI ultrashort‐TE …
The use of small animal imaging in respiratory disease drug discovery
The expansion of scientific knowledge and technology over the past decades did not result
in an increased rate of drug discoveries for respiratory diseases. Despite the identification of …
in an increased rate of drug discoveries for respiratory diseases. Despite the identification of …
Near‐infrared fluorescence imaging and histology confirm anomalous edematous signal distribution detected in the rat lung by MRI after allergen challenge
B Tigani, HU Gremlich, C Cannet… - Journal of Magnetic …, 2004 - Wiley Online Library
Purpose To address the issue concerning the predominant location, on the left anatomic
side, of edematous signals detected by magnetic resonance imaging (MRI) in the lungs of …
side, of edematous signals detected by magnetic resonance imaging (MRI) in the lungs of …