Crocin Improves Insulin Sensitivity and Ameliorates Adiposity by Regulating AMPK‐CDK5‐PPARγ Signaling
K Fang, M Gu - BioMed Research International, 2020 - Wiley Online Library
Crocin is a carotenoid compound which possesses multiple biological activities. Our and
other laboratory's previous findings show that crocin alleviates obesity and type 2 diabetes …
other laboratory's previous findings show that crocin alleviates obesity and type 2 diabetes …
Crocin inhibits obesity via AMPK-dependent inhibition of adipocyte differentiation and promotion of lipolysis
M Gu, L Luo, K Fang - Bioscience trends, 2018 - jstage.jst.go.jp
Obesity has become a severe public health problem worldwide. Crocin, a natural product,
has been reported to have a number of pharmacological activities, including …
has been reported to have a number of pharmacological activities, including …
[HTML][HTML] The effect of crocin supplementation on glycemic control, insulin resistance and active AMPK levels in patients with type 2 diabetes: a pilot study
V Behrouz, A Dastkhosh, M Hedayati… - Diabetology & metabolic …, 2020 - Springer
Background Crocin as a carotenoid exerts anti-oxidant, anti-inflammatory, anti-cancer,
neuroprotective and cardioprotective effects. Besides, the increasing prevalence of diabetes …
neuroprotective and cardioprotective effects. Besides, the increasing prevalence of diabetes …
[HTML][HTML] Crocin prevents metabolic syndrome in rats via enhancing PPAR-gamma and AMPK
MM Algandaby - Saudi Journal of Biological Sciences, 2020 - Elsevier
Metabolic syndrome (Mets) is a major health hazard. The syndrome is strongly linked to
cardiovascular disease. The objective of the current study was to address whether or not …
cardiovascular disease. The objective of the current study was to address whether or not …
[HTML][HTML] Modulating effects of crocin on lipids and lipoproteins: Mechanisms and potential benefits
H Yaribeygi, M Maleki, F Rashid-Farrokhi… - Heliyon, 2024 - cell.com
Dyslipidemia poses a significant risk to cardiovascular health in both diabetic and non-
diabetic individuals. Therefore, it is crucial to normalize lipid homeostasis in order to prevent …
diabetic individuals. Therefore, it is crucial to normalize lipid homeostasis in order to prevent …
Beneficial impact of crocetin, a carotenoid from saffron, on insulin sensitivity in fructose-fed rats
L Xi, Z Qian, G Xu, S Zheng, S Sun, N Wen… - The Journal of nutritional …, 2007 - Elsevier
Crocetin, a unique carotenoid with potent antioxidative and anti-inflammatory activities, is a
major ingredient of saffron which is used as an important spice and food colorant in various …
major ingredient of saffron which is used as an important spice and food colorant in various …
[HTML][HTML] Crocin ameliorates hepatic steatosis through activation of AMPK signaling in db/db mice
L Luo, K Fang, X Dan, M Gu - Lipids in health and disease, 2019 - Springer
Background Non-alcoholic fatty liver disease (NAFLD) is closely linked to obesity, type 2
diabetes and other metabolic disorders worldwide. Crocin is a carotenoid compound …
diabetes and other metabolic disorders worldwide. Crocin is a carotenoid compound …
Crocin molecular signaling pathways at a glance: A comprehensive review
M Boozari, H Hosseinzadeh - Phytotherapy Research, 2022 - Wiley Online Library
Crocin is a hydrophilic carotenoid that is synthesized in the flowers of the Crocus genus.
Numerous in vitro and in vivo research projects have been published about the biological …
Numerous in vitro and in vivo research projects have been published about the biological …
Crocin attenuates oxidative stress and inflammation in myocardial infarction induced by isoprenaline via PPARγ activation in diabetic rats
Background and purpose Hyperglycemia induced oxidative stress and inflammation lead to
development of diabetic cardiomyopathy. Diabetic patients are more at risk for myocardial …
development of diabetic cardiomyopathy. Diabetic patients are more at risk for myocardial …
Inhibitory effect on protein kinase Cθ by Crocetin attenuates palmitate-induced insulin insensitivity in 3T3-L1 adipocytes
Epidemiologic and experimental studies have pointed to an etiologic role of elevated
plasma free fatty acids in insulin resistance, which is frequently associated with a state of low …
plasma free fatty acids in insulin resistance, which is frequently associated with a state of low …