Effect from multiple episodes of inadequate empiric antibiotic therapy for ventilator-associated pneumonia on morbidity and mortality among critically ill trauma …

EW Mueller, SD Hanes, MA Croce… - Journal of Trauma …, 2005 - journals.lww.com
Background: Empiric antibiotic therapy is routinely initiated for patients with presumed
ventilator-associated pneumonia (VAP). The impact of inadequate empiric antibiotic therapy …

Reduction in inadequate empiric antibiotic therapy for ventilator-associated pneumonia: impact of a unit-specific treatment pathway

LJ Magnotti, TJ Schroeppel, TC Fabian… - The American …, 2008 - journals.sagepub.com
Empiric antibiotic therapy is routinely initiated for patients with presumed ventilator-
associated pneumonia (VAP). Reported mortality rates for inadequate empiric antibiotic …

Keeping it simple: impact of a restrictive antibiotic policy for ventilator-associated pneumonia in trauma patients on incidence and sensitivities of causative pathogens

CR Evans, JP Sharpe, JM Swanson, GC Wood… - Surgical …, 2018 - liebertpub.com
Background: An integral part of ventilator-associated pneumonia (VAP) therapy is the
appropriate choice of empiric antibiotics. Our previous experience demonstrated adherence …

Does de-escalation of antibiotic therapy for ventilator-associated pneumonia affect the likelihood of recurrent pneumonia or mortality in critically ill surgical patients?

SR Eachempati, LJ Hydo, J Shou… - Journal of Trauma and …, 2009 - journals.lww.com
Background: Ventilator-associated pneumonia (VAP) is a leading cause of mortality in
critically ill patients. Although previous studies have shown that de-escalation therapy (DT) …

Effects of empiric antibiotic administration for suspected pneumonia on subsequent opportunistic pulmonary infections

CS Koontz, MC Chang… - The American surgeon, 2000 - journals.sagepub.com
Optimal guidelines for empiric antibiotic (EAB) therapy in cases of suspected post-traumatic
ventilator-associated pneumonia (VAP) are not well defined. EAB administration is thought …

Evaluation of a clinical pathway for ventilator-associated pneumonia: changes in bacterial flora and the adequacy of empiric antibiotics over a three-year period

GC Wood, EW Mueller, MA Croce, BA Boucher… - Surgical …, 2005 - liebertpub.com
Background: Evaluation of causative pathogens is vital for optimizing empiric antibiotic
therapy of ventilator-associated pneumonia (VAP). Based on previous data (Ann Surg 1998; …

Causative pathogen dictates optimal duration of antimicrobial therapy for ventilator-associated pneumonia in trauma patients

LJ Magnotti, MA Croce, BL Zarzaur… - Journal of the American …, 2011 - Elsevier
Background Recent ventilator-associated pneumonia (VAP) guidelines recommend
considering abbreviated therapy in patients with non− Pseudomonas aeruginosa VAP if …

Use of the clinical pulmonary infection score to guide therapy for ventilator-associated pneumonia risks antibiotic overexposure in patients with trauma

NA Parks, LJ Magnotti, JA Weinberg… - Journal of Trauma …, 2012 - journals.lww.com
BACKGROUND The clinical pulmonary infection score (CPIS) has been advocated to guide
both the diagnosis and duration of therapy in ventilator-associated pneumonia (VAP) …

Risk factors for relapse of ventilator-associated pneumonia in trauma patients

EL Rangel, KL Butler, JA Johannigman… - Journal of Trauma …, 2009 - journals.lww.com
Background: Our goal was to define risk factors for ventilator-associated pneumonia (VAP)
relapse and examine the implications, if any, for initial therapy in trauma patients. Methods …

Reinventing the wheel: Impact of prolonged antibiotic exposure on multidrug-resistant ventilator-associated pneumonia in trauma patients

RH Lewis, JP Sharpe, JM Swanson… - Journal of Trauma …, 2018 - journals.lww.com
BACKGROUND Multidrug-resistant (MDR) strains of both Acinetobacter baumannii (AB) and
Pseudomonas aeruginosa (PA) as causative ventilator-associated pneumonia (VAP) …