The effects of acute exercise-induced cortisol on CCR2 expression on human monocytes

M Okutsu, K Suzuki, T Ishijima, J Peake… - Brain, behavior, and …, 2008 - Elsevier
CC-chemokine receptor 2 (CCR2) and its ligand, monocyte chemotactic protein-1 (MCP-1,
also known as CCL2), are crucial for the recruitment of monocytes/macrophages to sites of …

Distribution, cellular localization and functional role of CCR2 chemokine receptors in adult rat brain

G Banisadr, F Queraud‐Lesaux… - Journal of …, 2002 - Wiley Online Library
Recent studies demonstrated that the chemokine monocyte chemoattractant protein‐1 (MCP‐
1)/CCL2 and its receptor, CCR2, play important roles in various brain diseases. In this study …

Critical roles for CCR2 and MCP-3 in monocyte mobilization from bone marrow and recruitment to inflammatory sites

CL Tsou, W Peters, Y Si, S Slaymaker… - The Journal of …, 2007 - Am Soc Clin Investig
Monocyte recruitment to sites of inflammation is regulated by members of the chemokine
family of chemotactic cytokines. However, the mechanisms that govern the migration of …

Increase of CCR1 and CCR5 expression and enhanced functional response to MIP-1α during differentiation of human monocytes to macrophages

A Kaufmann, R Salentin, D Gemsa… - Journal of leukocyte …, 2001 - academic.oup.com
Chemokines and their receptors regulate migration of leukocytes under normal and
inflammatory conditions. In this study, we analyzed the CC chemokine receptor (CCR) …

Glucocorticoids enhance the in vivo migratory response of human monocytes

MP Yeager, PA Pioli, J Collins, F Barr, S Metzler… - Brain, behavior, and …, 2016 - Elsevier
Glucocorticoids (GCs) are best known for their potent anti-inflammatory effects. However, an
emerging model for glucocorticoid (GC) regulation of in vivo inflammation also includes a …

Cortisol-induced CXCR4 augmentation mobilizes T lymphocytes after acute physical stress

M Okutsu, K Ishii, KJ Niu… - American Journal of …, 2005 - journals.physiology.org
The aim of this study was to elucidate the mechanism responsible for lymphopenia after
exercise. Seven young healthy men volunteered for this study. Peripheral blood …

[HTML][HTML] Differential CCR1-mediated chemotaxis signaling induced by human CC chemokine HCC-4/CCL16 in HOS cells

IS Kim, SW Jang, HJ Sung, JS Lee, J Ko - FEBS letters, 2005 - Elsevier
Human CC chemokine-4 (HCC-4)/CCL16 is a chemoattractant for monocytes and
lymphocytes. Although HCC-4 binds to multiple CC chemokine receptors, the receptor …

Analysis of CCR2 splice variant expression patterns and functional properties

HK Park, YH Na, HT Nguyen, LP Nguyen, S Hurh… - Cell & Bioscience, 2022 - Springer
Background C–C motif chemokine receptor 2 (CCR2), the main receptor for monocyte
chemoattractant protein-1 (MCP-1), is expressed on immune cells, including monocytes …

Analysis of second messenger pathways stimulated by different chemokines acting at the chemokine receptor CCR5

K Leach, SJ Charlton, PG Strange - Biochemical pharmacology, 2007 - Elsevier
The chemokine receptor, CCR5, responds to several chemokines leading to changes in
activity in several signalling pathways. Here, we investigated the ability of different …

Differential expression of the isoforms for the monocyte chemoattractant protein-1 receptor, CCR2, in monocytes

S Tanaka, SR Green, O Quehenberger - Biochemical and biophysical …, 2002 - Elsevier
Two isoforms of human CCR2, the receptor for monocyte chemoattractant protein-1 (MCP-
1), have been identified but their relative expression in monocytes and contribution to …