Parkinson's disease (PD) is the second most common neurodegenerative disorder. It is
characterized by the accumulation of intracellular α-synuclein aggregates and the …

Background Metabolic perturbations and slower renewal of cellular components associated
with aging increase the risk of Parkinson's disease (PD). Declining activity of AMPK, a critical …

Currently there is no cure or effective disease-modifying therapy for Alzheimer's disease
(AD), the most common form of dementia that is becoming a global threat to public health. It …

Adenosine monophosphate-activated protein kinase (AMPK) is an evolutionarily conserved
sensor of cellular energy status and has been reported to be involved in chronic …

Alzheimer's disease, Parkinson's disease, Huntington's disease, and amyotrophic lateral
sclerosis are neurodegenerative disorders that are characterized by a progressive …

The AMP-activated protein kinase (AMPK) is a serine/threonine kinase that functions as a
key energy sensor in a wide variety of tissues. This kinase has been a major drug target for …

The adenosine monophosphate activated kinase protein (AMPK) is an evolutionary-
conserved protein important for cell survival and organismal longevity through the …

Maintaining proper energy levels in brain neurons is crucial for many cerebral functions
such as synaptic transmission, vesicle recycling and axonal transport. AMP-activated protein …

Simple Summary AMPK is an enzyme that plays a role in cellular energy mechanisms and
controls many metabolic and physiological processes. AMPK is dysregulated in different …

Alzheimer's disease is a multifactorial neurodegenerative disease characterized by
progressive cognitive dysfunction. It is the most common form of dementia. The pathologic …