Superoxide dismutase as multipotent therapeutic antioxidant enzyme: Role in human diseases

P Saxena, K Selvaraj, SK Khare, N Chaudhary - Biotechnology letters, 2022 - Springer
Reactive oxygen species (ROS) is consistently recognized as a threat to living organisms,
especially for human beings. For proper working of cellular signaling, functioning, and …

[HTML][HTML] Therapeutic potentials of superoxide dismutase

H Younus - International journal of health sciences, 2018 - ncbi.nlm.nih.gov
Superoxide dismutases (SODs) constitute a very important antioxidant defense against
oxidative stress in the body. The enzyme acts as a good therapeutic agent against reactive …

The basic and applied aspects of superoxide dismutase

A Bafana, S Dutt, A Kumar, S Kumar… - Journal of Molecular …, 2011 - Elsevier
Superoxide dismutase (SOD) is among the most potent antioxidants known in nature and is
an important constituent of cellular defence against oxidative stress. The enzyme shows …

The applications and mechanisms of superoxide dismutase in medicine, food, and cosmetics

M Zheng, Y Liu, G Zhang, Z Yang, W Xu, Q Chen - Antioxidants, 2023 - mdpi.com
Superoxide dismutase (SOD) is a class of enzymes that restrict the biological oxidant cluster
enzyme system in the body, which can effectively respond to cellular oxidative stress, lipid …

Superoxide dismutases (SODs) and SOD mimetics

GEO Borgstahl, RE Oberley-Deegan - Antioxidants, 2018 - mdpi.com
Superoxide dismutase (SOD) is the only known enzyme to directly scavenge a free radical.
Specifically, SOD dismutes superoxide to oxygen and hydrogen peroxide with high …

SOD, oxidative stress and human pathologies: a brief history and a future vision

JM McCord, MA Edeas - Biomedicine & Pharmacotherapy, 2005 - Elsevier
Superoxide dismutase (SOD) has now been known for 35 years. While the superoxide
radical and SOD have been implicated in many disease states including inflammatory …

Superoxide dismutase: an updated review on its health benefits and industrial applications

MN Islam, A Rauf, FI Fahad, TB Emran… - Critical Reviews in …, 2022 - Taylor & Francis
Many short-lived and highly reactive oxygen species, such as superoxide anion (O2-) and
hydrogen peroxide (H2O2), are toxic or can create oxidative stress in cells, a response …

Superoxide dismutase: an emerging target for cancer therapeutics

EA Hileman, G Achanta, P Huang - Expert Opinion on Therapeutic …, 2001 - Taylor & Francis
Superoxide dismutase (SOD) is a critical enzyme responsible for the elimination of
superoxide radicals and is considered to be a key anti-oxidant in aerobic cells. Cellular …

Superoxide dismutase administration, a potential therapy against oxidative stress related diseases: several routes of supplementation and proposal of an original …

J Carillon, JM Rouanet, JP Cristol, R Brion - Pharmaceutical research, 2013 - Springer
Oxidative stress, involved in many diseases, is defined as an impaired balance between
reactive oxygen species (ROS) production and antioxidant defences. Antioxidant enzymes …

Superoxide dismutase: the balance between prevention and induction of oxidative damage

GJM den Hartog, GRMM Haenen, E Vegt… - Chemico-biological …, 2003 - Elsevier
Cu, Zn-superoxide dismutase (SOD1) has been shown to be effective in several free radical
mediated diseases, although some studies have pointed toward SOD1 toxicity at a high …