Matrix-binding isoforms and non-matrix-binding isoforms of vascular endothelial growth
factor (VEGF) are both capable of stimulating vascular remodeling, but the resulting blood …

The splice isoforms of vascular endothelial growth A (VEGF) each have different affinities for
the extracellular matrix (ECM) and the coreceptor NRP1, which leads to distinct vascular …

The dynamic nanoscale organization of cell surface receptors plays an important role in
signaling. We determine this organization and its relation to activation of VEGF receptor-2 …

The vascular endothelial growth factor receptors (VEGFR) play a significant role in
angiogenesis, the formation of new blood vessels from existing vasculature. Systems …

Vascular endothelial growth factor (VEGF) signal transduction through the cell surface
receptors VEGFR1 and VEGFR2 regulates angiogenesis—the growth of new capillaries …

Several cytokine families have roles in the development, maintenance, and remodeling of
the microcirculation. Of these, the vascular endothelial growth factor (VEGF) family is one of …

Vascular endothelial growth factors (VEGFs) bind to membrane receptors on a wide variety
of cells to regulate diverse biological responses. The VEGF-A family member promotes …

Most physiological processes are subjected to molecular regulation by growth factors, which
are secreted proteins that activate chemical signal transduction pathways through binding of …

Background The spatial distribution of vascular endothelial growth factor A (VEGF) is an
important mediator of vascular patterning. Previous experimental studies in the mouse …

Vascular endothelial growth factor A (VEGF-A) binding to the receptor tyrosine kinase
VEGFR2 triggers multiple signal transduction pathways, which regulate endothelial cell …