Background: A previous study using a sipper procedure of ethanol self‐administration found
that blockade of the D2 dopamine (DA) receptors in the nucleus accumbens resulted in a …

Background: Nucleus accumbens dopamine has been shown to play a role in the
processing of behaviorally relevant stimuli and to mediate ethanol‐reinforced responding …

One of the functions of the mesolimbic dopamine (DA) system is to regulate the process of
reinforcement, a process that is thought to influence drug self‐administration. This study …

It was determined whether ethanol palatability in rats could be changed by manipulating the
reinforcement experienced during limited access consumption. During the first 3 days of the …

Rats initiated to self-administer 10% ethanol (v/v) in an operant situation using the sucrose-
substitution technique received bilateral n. accumbens or caudate nucleus microinjections of …

From previous microinjection studies, a reciprocal feedback between the nucleus
accumbens and the ventral tegmental area (VTA) has been implicated in the reinforcing …

Remoxipride, a dopamine D2 antagonist, decreases responding that results in the
presentation of small amounts (~ 0.1 ml) of ethanol in limited-access paradigms. This type of …

The complex mesolimbic–mesocortical system involved with behavioral selection has been
implicated in the control of ethanol self-administration. However, the nature of the …

The present experiment tested the effects of intraaccumbens injections of dopamine (DA)
agonists and antagonists on operant responding reinforced by sucrose and sucrose/ethanol …

The opiate antagonist naltrexone suppresses ethanol-reinforced behavior in animals and
decreases ethanol intake in humans. However, the mechanisms underlying these actions …