A growing body of evidence has drawn the attention of the scientific community by indicating
the potential vulnerability to environmental changes of epigenetic mechanisms that control …

Epigenetics is an intrinsic mechanism that alters gene function–not by altering DNA
sequences, but by chemically modifying the DNA and chromosomal histone proteins …

Complex phenotypes result from the interaction between genetic and environmental
informations. Almost a decade ago, the discovery of acquired epigenetic inheritance has …

The main objective of this conference was to provide solid evidence that environmental
exposures during early development can affect faithful reproduction of individual parental …

Epidemiological evidence increasingly suggests that environmental exposures early in
development have a role in susceptibility to disease in later life. In addition, some of these …

The effects of environmental factors and epigenetics on health and disease development
are complex and interconnected. Environmental factors encompass external influences like …

Abstract Purpose of Review Epigenetic processes represent important mechanisms
underlying developmental plasticity in response to environmental exposures. The current …

This review focuses on how environmental factors through epigenetics modify disease risk
and health outcomes. Major epigenetic events, such as histone modifications, DNA …

In the spring of 1998 my co-editor, colleague and friend, Randy Jirtle, approached me at a
scientific meeting in San Diego, CA to discuss something that clearly had him excited …

The epigenetic profile of an individual is built in part through an intrinsic program including
an inherited template and acquired environmental inputs throughout the lifespan. The latter …