Improved neutralisation of the SARS-CoV-2 Omicron variant following a booster dose of Pfizer-BioNTech (BNT162b2) COVID-19 vaccine

K Basile, RJ Rockett, K McPhie, M Fennell… - Viruses, 2022 - mdpi.com
In late November 2021, the World Health Organization declared the SARS-CoV-2 lineage B.
1.1. 529 the fifth variant of concern, Omicron. This variant has acquired over 30 mutations in …

[HTML][HTML] SARS-CoV-2 Omicron neutralization by therapeutic antibodies, convalescent sera, and post-mRNA vaccine booster

S Lusvarghi, SD Pollett, SN Neerukonda, W Wang… - BioRxiv, 2021 - ncbi.nlm.nih.gov
The rapid spread of the highly contagious Omicron variant of SARS-CoV-2 along with its
high number of mutations in the spike gene has raised alarm about the effectiveness of …

[HTML][HTML] Booster of mRNA-1273 strengthens SARS-CoV-2 Omicron neutralization

NA Doria-Rose, X Shen, SD Schmidt, S O'Dell… - MedRxiv, 2021 - ncbi.nlm.nih.gov
The Omicron variant of SARS-CoV-2 is raising concerns because of its increased
transmissibility and potential for reduced susceptibility to antibody neutralization. To assess …

[HTML][HTML] T cell reactivity to the SARS-CoV-2 Omicron variant is preserved in most but not all individuals

V Naranbhai, A Nathan, C Kaseke, C Berrios, A Khatri… - Cell, 2022 - cell.com
Summary The SARS-CoV-2 Omicron variant (B. 1.1. 529) contains mutations that mediate
escape from antibody responses, although the extent to which these substitutions in spike …

Durable spike-specific T cell responses after different COVID-19 vaccination regimens are not further enhanced by booster vaccination

Y Maringer, A Nelde, SM Schroeder… - Science …, 2022 - science.org
Several COVID-19 vaccines are approved to prevent severe disease outcome after SARS-
CoV-2 infection. Whereas induction and functionality of antiviral antibody response are …

Long-lasting T cell responses in BNT162b2 COVID-19 mRNA vaccinees and COVID-19 convalescent patients

A Hurme, P Jalkanen, J Heroum, O Liedes… - Frontiers in …, 2022 - frontiersin.org
The emergence of novel variants of the severe acute respiratory syndrome coronavirus 2
(SARS-CoV-2) has made it more difficult to prevent the virus from spreading despite …

Two doses of the SARS-CoV-2 BNT162b2 vaccine enhance antibody responses to variants in individuals with prior SARS-CoV-2 infection

RA Urbanowicz, T Tsoleridis, HJ Jackson… - Science translational …, 2021 - science.org
Understanding the impact of prior infection with severe acute respiratory syndrome
coronavirus 2 (SARS-CoV-2) on the response to vaccination is a priority for responding to …

[HTML][HTML] Neutralization of SARS-CoV-2 Omicron sub-lineages BA. 1, BA. 1.1, and BA. 2

JP Evans, C Zeng, P Qu, J Faraone, YM Zheng… - Cell host & …, 2022 - cell.com
Recent reports of SARS-CoV-2 Omicron variant sub-lineages, BA. 1, BA. 1.1, and BA. 2,
have reignited concern over potential escape from vaccine-and infection-induced immunity …

Neutralisation sensitivity of the SARS-CoV-2 omicron (B. 1.1. 529) variant: a cross-sectional study

DJ Sheward, C Kim, RA Ehling, A Pankow… - The Lancet Infectious …, 2022 - thelancet.com
Summary Background The SARS-CoV-2 omicron (B. 1.1. 529) variant, which was first
identified in November, 2021, spread rapidly in many countries, with a spike protein highly …

[HTML][HTML] SARS-CoV-2 Omicron Spike recognition by plasma from individuals receiving BNT162b2 mRNA vaccination with a 16-week interval between doses

D Chatterjee, A Tauzin, L Marchitto, SY Gong, M Boutin… - Cell reports, 2022 - cell.com
Continuous emergence of SARS-CoV-2 variants of concern (VOCs) is fueling the COVID-19
pandemic. Omicron (B. 1.1. 529) rapidly spread worldwide. The large number of mutations in …