Abstract The tea polyphenol (−)-epigallocatechin-3-gallate (EGCG) has been reported to act
as a cancer preventive agent through folate pathway inhibition in experimental studies. We …

Folate plays an important role in DNA methylation, synthesis, and repair; intake has been
associated with breast cancer. The folate-metabolizing enzyme, methylenetetrahydrofolate …

Although many in vitro and animal studies have suggested a protective effect of green tea
against breast cancer, only a few epidemiological studies have examined this association …

To evaluate the relationship between dietary folate intake and genetic polymorphisms of 5,
10-methylenetetrahydrofolate reductase (MTHFR) with reference to breast cancer risk, we …

This study aimed to examine the joint effects of folate intake, polymorphisms of 5, 10-
methylenetetrahydrofolate reductase (MTHFR), methionine synthesis reductase (MTRR) and …

Green tea is a commonly consumed beverage in China. Epidemiological and animal data
suggest tea and tea polyphenols may be preventive against various cancers, including …

Breast cancer is the most common malignancy in women worldwide. Tea has
anticarcinogenic effects against breast cancer in experimental studies. However …

Accumulating evidence from epidemiologic studies suggests that risk of breast cancer is
reduced in relation to increased consumption of folate and related B vitamins. We …

Methylenetetrahydrofolate reductase (MTHFR) is a key regulatory enzyme in the metabolism
of folate, a nutrient which has recently been found to be inversely related to breast cancer in …

We conducted a hospital-based case-control study to investigate the associations of dietary
intake of folate and MTHFR C677T and A1298C polymorphisms with breast cancer in a …