The lens is an avascular organ in which gap junctions play a pivotal role for cell physiology
and transparency. Here we evaluate a lens culture system as a model for studies of lens gap …

purpose. The present study was undertaken to explore the roles gap junctions play in lens
epithelial cell differentiation. methods. Recombinant retroviruses expressing three chick lens …

PURPOSE: To study in both in situ and primary cultures the posttranslational
phosphorylation of connexin46 (Cx46), one of two members of the connexin family of gap …

PURPOSE: To characterize the chicken lens gap junction protein, connexin56 (Cx56).
METHODS: The methods used were immunoblotting, immunofluorescence, alkaline …

Intercellular communication mediated by gap junctions is important for tissue homeostasis in
the avascular lens, and extensive areas of gap junctions form between fiber cells during …

To examine the effects of increased expression of Cx50 in the mouse lens, transgenic mice
were generated using a DNA construct containing the human Cx50 coding region and a C …

A major limitation in lens gap junction research has been the lack of experimentally tractable
ex vivo systems to study the formation and regulation of fiber-type gap junctions. Although …

PURPOSE: This study was performed to determine whether the junctions between both the
epithelial and the differentiating fiber-like cells of ovine lens cultures, like gap junctions in …

The avian lens is an ideal system to study gap junctional intercellular communication in
development and homeostasis. The lens is experimentally more accessible in the …

PURPOSE: To investigate the role of the gap junction protein connexin43 (Cx43), which is
predominantly expressed in lens epithelial cells in the control of lens development and …