Structural and functional diversity of native brain neuronal nicotinic receptors

C Gotti, F Clementi, A Fornari, A Gaimarri… - Biochemical …, 2009 - Elsevier
Neuronal nicotinic acetylcholine receptors (nAChRs) are a family of ligand-gated ion
channels present in the central and peripheral nervous systems, that are permeable to mono …

Diversity of native nicotinic receptor subtypes in mammalian brain

M Zoli, F Pistillo, C Gotti - Neuropharmacology, 2015 - Elsevier
Neuronal nicotinic acetylcholine receptors (nAChRs) are a heterogeneous family of
pentameric ligand-gated cation channels that are expressed throughout the brain and …

Brain neuronal nicotinic receptors as new targets for drug discovery

C Gotti, L Riganti, S Vailati… - Current pharmaceutical …, 2006 - ingentaconnect.com
Neuronal nicotinic receptors (nAChRs) are a heterogeneous family of ion channels
differently expressed in the nervous system where, by responding to the endogenous …

Neuronal nicotinic receptors in the human brain

D Paterson, A Nordberg - Progress in neurobiology, 2000 - Elsevier
Neuronal nicotinic acetylcholine receptors (nAChRs) are a family of ligand gated ion
channels which are widely distributed in the human brain. Multiple subtypes of these …

Human neuronal nicotinic receptors

C Gotti, D Fornasari, F Clementi - Progress in neurobiology, 1997 - Elsevier
Nicotine is a very widely used drug of abuse, which exerts a number of neurovegetative,
behavioural and psychological effects by interacting with neuronal nicotinic acetylcholine …

Neuronal nicotinic receptors: from structure to pathology

C Gotti, F Clementi - Progress in neurobiology, 2004 - Elsevier
Neuronal nicotinic receptors (NAChRs) form a heterogeneous family of ion channels that are
differently expressed in many regions of the central nervous system (CNS) and peripheral …

Nicotinic acetylcholine receptors and nicotinic cholinergic mechanisms of the central nervous system

JA Dani, D Bertrand - Annu. Rev. Pharmacol. Toxicol., 2007 - annualreviews.org
Subtypes of neuronal nicotinic acetylcholine receptors (nAChRs) are constructed from
numerous subunit combinations that compose channel-receptor complexes with varied …

Molecular diversity of neuronal nicotinic acetylcholine receptors

DS McGEHEE - Annals of the New York Academy of Sciences, 1999 - Wiley Online Library
The potent behavioral and cognitive effects of nicotine highlight the physiological
importance of nicotinic acetylcholine receptors (nAChRs). These receptors are part of the …

Neuronal nicotinic acetylcholine receptor structure and function and response to nicotine

JA Dani - International review of neurobiology, 2015 - Elsevier
Nicotinic acetylcholine receptors (nAChRs) belong to the “Cys-loop” superfamily of ligand-
gated ion channels that includes GABA A, glycine, and serotonin (5-HT 3) receptors. There …

[HTML][HTML] Mammalian nicotinic acetylcholine receptors: from structure to function

EX Albuquerque, EFR Pereira… - Physiological …, 2009 - journals.physiology.org
The classical studies of nicotine by Langley at the turn of the 20th century introduced the
concept of a “receptive substance,” from which the idea of a “receptor” came to light …