ExoDS: a versatile exosome-based drug delivery platform to target cancer cells and cancer stem cells

S Paul, S Bhagat, L Dash, HD Mohapatra… - … in Bioengineering and …, 2024 - frontiersin.org
Chemotherapy drugs like doxorubicin (Dox) are widely used in middle-income countries
around the world to treat various types of cancers, including breast cancer. Although they …

[HTML][HTML] Exosomes as drug carriers in anti-cancer therapy

L Chen, L Wang, L Zhu, Z Xu, Y Liu, Z Li… - Frontiers in Cell and …, 2022 - frontiersin.org
Over the years, there has been a high demand for developing new safe and effective drug
carriers for cancer therapy. Emerging studies have indicated that exosomes can serve as …

[HTML][HTML] Tumor cell-derived exosomes home to their cells of origin and can be used as Trojan horses to deliver cancer drugs

L Qiao, S Hu, K Huang, T Su, Z Li, A Vandergriff… - Theranostics, 2020 - ncbi.nlm.nih.gov
Cancer is the second leading cause of death worldwide and patients are in urgent need of
therapies that can effectively target cancer with minimal off-target side effects. Exosomes are …

Targeted doxorubicin-loaded mesenchymal stem cells-derived exosomes as a versatile platform for fighting against colorectal cancer

E Bagheri, K Abnous, SA Farzad, SM Taghdisi… - Life sciences, 2020 - Elsevier
Exosomes hold great potential for cancer treatment to deliver therapeutics due to its inherent
low immunogenicity. Exosomes are biocompatible cell-exocytosed secreted vesicles by …

[HTML][HTML] Exosomes: cell-derived nanoplatforms for the delivery of cancer therapeutics

H Kim, EH Kim, G Kwak, SG Chi, SH Kim… - International journal of …, 2020 - mdpi.com
Exosomes are cell-secreted nanovesicles that naturally contain biomolecular cargoes such
as lipids, proteins, and nucleic acids. Exosomes mediate intercellular communication …

[HTML][HTML] Exosomes and mimics as novel delivery platform for cancer therapy

F Yang, M Wang, X Guan - Frontiers in Pharmacology, 2022 - frontiersin.org
Exosomes are nano-sized biological extracellular vesicles transmitting information between
cells and constituting a new intercellular communication mode. Exosomes have many …

Targeted cancer therapy using engineered exosome as a natural drug delivery vehicle

H Gomari, M Forouzandeh Moghadam… - OncoTargets and …, 2018 - Taylor & Francis
Purpose Exosomes are small 30–100 nm vesicles secreted by various cell types. They are
released by most cell types, indicating their important role in physiological and pathological …

[HTML][HTML] Strategies to overcome the main challenges of the use of exosomes as drug carrier for cancer therapy

BM Hussen, GSH Faraj, MF Rasul, HJ Hidayat… - Cancer Cell …, 2022 - Springer
Exosomes are naturally occurring nanosized particles that aid intercellular communication
by transmitting biological information between cells. Exosomes have therapeutic efficacy …

[HTML][HTML] Engineering exosomes: a new direction for anticancer treatment

B You, W Xu, B Zhang - American journal of cancer research, 2018 - ncbi.nlm.nih.gov
Currently, lacks of specificity and effectiveness remain the main drawbacks of clinical cancer
treatment. Despite therapeutic advances in recent decades, clinical outcomes remain poor …

Stem Cell-Derived Exosomes: An Advanced Horizon to Cancer Regenerative Medicine

A Ramachandran, R Dhar, A Devi - ACS Applied Bio Materials, 2024 - ACS Publications
Cancer research has made significant progress in recent years, and extracellular vesicles
(EVs) based cancer investigation reveals several facts about cancer. Exosomes are a …