Improved T2* assessment in liver iron overload by magnetic resonance imaging
V Positano, B Salani, A Pepe, MF Santarelli… - Magnetic resonance …, 2009 - Elsevier
In the clinical MRI practice, it is common to assess liver iron overload by T2* multi-echo
gradient-echo images. However, there is no full consensus about the best image analysis …
gradient-echo images. However, there is no full consensus about the best image analysis …
Liver MRI is more precise than liver biopsy for assessing total body iron balance: a comparison of MRI relaxometry with simulated liver biopsy results
JC Wood, P Zhang, H Rienhoff, W Abi-Saab… - Magnetic resonance …, 2015 - Elsevier
Purpose Liver biopsy was long considered the reference standard for measuring liver iron
concentration. However, its high sampling variability and invasive nature make it poorly …
concentration. However, its high sampling variability and invasive nature make it poorly …
Hepatic iron overload: diagnosis and quantification with MR imaging.
O Ernst, G Sergent, P Bonvarlet… - … American journal of …, 1997 - Am Roentgen Ray Soc
The aim of this study was to assess the sensitivity of MR imaging in the diagnosis of liver
hemochromatosis and its ability to quantify hepatic iron concentration (HIC). MR images …
hemochromatosis and its ability to quantify hepatic iron concentration (HIC). MR images …
R2* magnetic resonance imaging of the liver in patients with iron overload
R2* magnetic resonance imaging (R2*-MRI) can quantify hepatic iron content (HIC) by
noninvasive means but is not fully investigated. Patients with iron overload completed 1.5 T …
noninvasive means but is not fully investigated. Patients with iron overload completed 1.5 T …
Single region of interest versus multislice T2* MRI approach for the quantification of hepatic iron overload
A Meloni, A Luciani, V Positano… - Journal of Magnetic …, 2011 - Wiley Online Library
Purpose To evaluate the effectiveness of the single ROI approach for the detection of
hepatic iron burden in thalassemia major (TM) patients in respect to a whole liver …
hepatic iron burden in thalassemia major (TM) patients in respect to a whole liver …
Magnetic resonance imaging quantification of liver iron
Hepatic iron overload is the abnormal and excessive intracellular accumulation of iron in
hepatocytes, Kupffer cells, or both hepatocytes and Kupffer cells, primarily as ferritin …
hepatocytes, Kupffer cells, or both hepatocytes and Kupffer cells, primarily as ferritin …
Quantitative susceptibility mapping (QSM) minimizes interference from cellular pathology in R2* estimation of liver iron concentration
Background A challenge for R2 and R2* methods in measuring liver iron concentration (LIC)
is that fibrosis, fat, and other hepatic cellular pathology contribute to R2 and R2* and …
is that fibrosis, fat, and other hepatic cellular pathology contribute to R2 and R2* and …