[HTML][HTML] Clinical and molecular markers in COPD

I Gonçalves, MJ Guimarães, M Van Zeller, F Menezes… - Pulmonology, 2018 - Elsevier
Chronic obstructive pulmonary disease (COPD) is a complex and heterogeneous disease,
and there is a clinical need for validated markers and biomarkers that can contribute to the …

COPD phenotypes and biomarkers: Introducing personalised medicine

AG Mathioudakis… - Current Respiratory …, 2013 - ingentaconnect.com
Chronic Obstructive Pulmonary Disease (COPD) is a leading cause of morbidity and
mortality worldwide. Disease severity evaluation was based on airflow limitation for many …

Biomarkers in chronic obstructive pulmonary disease: the gateway to precision medicine

S Milne, DD Sin - Clinics in Chest Medicine, 2020 - chestmed.theclinics.com
Chronic obstructive pulmonary disease (COPD) is a progressive disease of the lung
characterized by irreversible airflow obstruction, persistent airway inflammation, and …

Current approaches for phenotyping as a target for precision medicine in COPD management

JL Lopez-Campos, S Centanni - COPD: Journal of Chronic …, 2018 - Taylor & Francis
The study of airway diseases continues to present several challenges for modern medicine.
The different disease presentations with variables and overlapping features may result in a …

The challenges of precision medicine in COPD

M Cazzola, L Calzetta, P Rogliani… - Molecular diagnosis & …, 2017 - Springer
Pheno-/endotyping chronic obstructive pulmonary disease (COPD) is really important
because it provides patients with precise and personalized medicine. The central concept of …

COPD phenotyping

SA Christenson - Respiratory Care, 2023 - rc.rcjournal.com
COPD is a heterogeneous condition, the onset and trajectory of which is influenced not only
by tobacco exposure but also an individual's genetics and the exposures they accumulate …

Personalized medicine and chronic obstructive pulmonary disease

EFM Wouters, B Wouters, IML Augustin… - Current opinion in …, 2017 - journals.lww.com
Personalized medicine and chronic obstructive pulmonary dise... : Current Opinion in
Pulmonary Medicine Personalized medicine and chronic obstructive pulmonary disease …

Phenotyping before starting treatment in COPD?

N Siafakas, A Corlateanu, E Fouka - COPD: Journal of Chronic …, 2017 - Taylor & Francis
ABSTRACT Chronic Obstructive Pulmonary Disease (COPD) is a heterogeneous and
complex disease with great morbidity and mortality. Despite the new developments in the …

Biomarker development for chronic obstructive pulmonary disease. From discovery to clinical implementation

DD Sin, Z Hollander, ML DeMarco… - American journal of …, 2015 - atsjournals.org
Chronic obstructive pulmonary disease (COPD) is one of the major causes of morbidity and
mortality in the world. Regrettably, there are no biomarkers to objectively diagnose COPD …

Biomarkers in chronic obstructive pulmonary disease

DD Sin, J Vestbo - Proceedings of the American Thoracic Society, 2009 - atsjournals.org
Currently, with exception of lung function tests, there are no well validated biomarkers or
surrogate endpoints that can be used to establish efficacy of novel drugs for chronic …