The role of oxidative stress in causing liver diseases emerged in the early 1960s from the
laboratories of Trevor Slater, Mario Umberto Dianzani and others. These pioneering works …

Oxidative stress and liver injury are strongly associated. Oxidative stress in the liver can be
triggered during different conditions and by specific etiologies, including hepatotoxins …

Oxidative stress is an unavoidable consequence of life in an oxygen-rich atmosphere.
Reactive oxygen species (ROS) and reactive nitrogen species (RNS) are generated as by …

Oxidative stress is a major pathogenetic event occurring in several liver disorders ranging
from metabolic to proliferative ones, and is a major cause of liver damage due to …

This chapter describes the implication of oxidative stress in the progression of the liver
diseases with higher prevalence worldwide: nonalcoholic fatty liver disease, cholestasis …

Oxygen is vital for life as it is required for many different enzymatic reactions involved in
intermediate metabolism and xenobiotic biotransformation. Moreover, oxygen consumption …

The role of oxidative stress and related reactive intermediates has been discussed,
including reactive oxygen species, aldehydic end-products of lipid peroxidation such as 4 …

THE IMPORTANCE OF REACTIVE OXYGEN SPECIES is well recognized in a number of
liver diseases, including inflammatory conditions. However, the molecular mechanisms have …

The inflammatory response is of prime importance in liver disease, irrespective of inciting
cause, and is inextricably linked to oxidative stress and the generation of reactive oxygen …

Electron fluxes are constant within cellular metabolism. Donating or accepting electrons,
either naked or as hydrogen atoms, is one of the most important properties of bioenergetic …