In psoriasis lesions, a diverse mixture of cytokines is up-regulated that influence each other
generating a complex inflammatory situation. Although this is the case, the inhibition of IL …

Psoriasis is a chronic inflammatory skin disease resulting from genetic, epigenetic,
environmental, and lifestyle factors. To date, several immunopathogenic mechanisms of …

A key challenge in psoriasis therapy is the tendency for lesions to recur in previously
affected anatomical locations after treatment discontinuation following lesion resolution …

Psoriasis is a chronic, immune‐mediated disease affecting more than 100 million people
worldwide and up to 2.2% of the UK population. The aetiology of psoriasis is thought to …

Psoriasis is a complex long-lasting inflammatory skin disease with high prevalence and
associated comorbidity. It is characterized by epidermal hyperplasia and dermal infiltration …

Psoriasis is one of the most common immune-mediated chronic, inflammatory skin diseases
characterized by hyperproliferative keratinocytes and infiltration of T cells, dendritic cells …

Introduction: Psoriasis is an autoimmune skin disease characterized by red plaques with
silver or white multilayered scales with a thickened acanthotic epidermis. Using mouse …

The exact pathogenesis of plaque psoriasis remains to be fully determined, but it is thought
to depend on environmental and genetic factors that stimulate dysregulated innate and …

The study of psoriasis has yielded fundamental new insights into immunologic regulation
and innovative therapies in a way that few other diseases have. In this review, we …

Chronic and excessive inflammation in skin and joints causes significant morbidity in
psoriasis patients. As a prevalent T lymphocyte–mediated disorder, psoriasis, as well as the …