[HTML][HTML] Tunneling nanotube (TNT) formation is downregulated by cytarabine and NF-κB inhibition in acute myeloid leukemia (AML)

M Omsland, Ø Bruserud, BT Gjertsen, V Andresen - Oncotarget, 2017 - ncbi.nlm.nih.gov
Acute myeloid leukemia (AML) is a bone marrow derived blood cancer where intercellular
communication in the leukemic bone marrow participates in disease development …

Specialized intercellular communications via tunnelling nanotubes in acute and chronic leukemia

A Allegra, M Di Gioacchino, G Cancemi, M Casciaro… - Cancers, 2022 - mdpi.com
Simple Summary Tunneling nanotubes (TNTs) are cytoplasmic channels which regulate the
contacts between cells and allow the transfer of several elements, including ions …

[HTML][HTML] INTERFERON ALPHA AND TYROSINE KINASE INHIBITORS INCREASE TUNNELING NANOTUBES (TNT) FORMATION AND CELL ADHESION IN …

M Omsland, V Andresen, SE Gullaksen… - … : official publication of …, 2020 - ncbi.nlm.nih.gov
Chronic myeloid leukemia (CML) is a stem cell disease of the bone marrow where
mechanisms of inter-leukemic communication and cell-to-cell interactions are proposed to …

B-cell precursor acute lymphoblastic leukemia cells use tunneling nanotubes to orchestrate their microenvironment

R Polak, B de Rooij, R Pieters… - Blood, The Journal of …, 2015 - ashpublications.org
Acute lymphoblastic leukemia (ALL) cells reside in the bone marrow microenvironment
which nurtures and protects cells from chemotherapeutic drugs. The disruption of cell-cell …

Tunneling nanotubes facilitate autophagosome transfer in the leukemic niche

B de Rooij, R Polak, F Stalpers, R Pieters… - Leukemia, 2017 - nature.com
Acute lymphoblastic leukemia (ALL) cells disrupt the healthy bone marrow
microenvironment to create a leukemic niche that is crucial for facilitating leukemogenesis …

Tunneling nanotubes: The intercellular conduits contributing to cancer pathogenesis and its therapy

PK Melwani, BN Pandey - Biochimica et Biophysica Acta (BBA)-Reviews …, 2023 - Elsevier
Tunneling nanotubes (TNTs) are intercellular conduits, which meet the communication
needs of non-adjacent cells situated in the same tissue but at distances up to a few hundred …

Tunneling nanotubes, a novel mode of tumor cell–macrophage communication in tumor cell invasion

SJ Hanna, K McCoy-Simandle, E Leung… - Journal of cell …, 2019 - journals.biologists.com
The interaction between tumor cells and macrophages is crucial in promoting tumor invasion
and metastasis. In this study, we examined a novel mechanism of intercellular …

Tunneling nanotubes: a versatile target for cancer therapy

P Sahu, SR Jena, L Samanta - Current Cancer Drug Targets, 2018 - ingentaconnect.com
Currently Cancer is the leading cause of death worldwide. Malignancy or cancer is a class of
diseases characterized by uncontrolled cell growth that eventually invade other tissues and …

Chemotherapy-induced tunneling nanotubes mediate intercellular drug efflux in pancreatic cancer

S Desir, P O'Hare, RI Vogel, W Sperduto, A Sarkari… - Scientific reports, 2018 - nature.com
Intercellular communication plays a critical role in the ever-evolving landscape of invasive
cancers. Recent studies have elucidated the potential role of tunneling nanotubes (TNTs) in …

Cell communication by tunneling nanotubes: Implications in disease and therapeutic applications

R Mittal, E Karhu, JS Wang, S Delgado… - Journal of cellular …, 2019 - Wiley Online Library
Intercellular communication is essential for the development and maintenance of
multicellular organisms. Tunneling nanotubes (TNTs) are a recently recognized means of …