Leveraging innovative therapies with an evolving understanding of the molecular pathogenesis of penile squamous cell carcinoma

A Hajiran, T Bracco, L Zemp, PE Spiess - Urologic Oncology: Seminars and …, 2022 - Elsevier
Penile squamous cell carcinoma is a rare condition that is associated with significant
morbidity and mortality in its advanced stages. In today's rapidly evolving field of oncology …

Future directions in advanced penile cancer–mechanisms of carcinogenesis and a search for targeted therapy

J Teh, E O'Connor, J O'Brien, WM Lim, M Taylor… - Future …, 2020 - Future Medicine
Penile squamous cell carcinoma (SCC) is a rare and aggressive urological malignancy.
Advanced penile SCC requires multimodal management, including surgery and systemic …

The molecular pathogenesis of penile carcinoma—current developments and understanding

A Emmanuel, J Nettleton, N Watkin, DM Berney - Virchows Archiv, 2019 - Springer
Penile squamous cell carcinoma is a rare malignancy with various distinct histological
subtypes, each with distinct appearances, histotypic specific associations with human …

Advances in understanding of penile carcinogenesis: the search for actionable targets

J Chipollini, S Chaing, M Azizi, LC Kidd, P Kim… - International journal of …, 2017 - mdpi.com
Penile cancer (PeCa) is a rare malignancy with potentially devastating effects. Squamous
cell carcinoma is the most common variant with distinct precancerous lesions before …

Mechanism of Carcinogenesis and Progression

G Vos, L Elst, M Albersen - Penile Carcinoma: Therapeutic Principles and …, 2021 - Springer
Penile cancer is a rare malignancy that is characterized by early lymphatic spread and a
poor prognosis in advanced disease. Due to the rarity of the disease, at present, our …

Updates in the molecular epidemiology and systemic approaches to penile cancer

JJ Adashek, A Necchi, PE Spiess - Urologic Oncology: Seminars and …, 2019 - Elsevier
Penile cancer is a rare, but increasingly more common diagnosis. Although more there are
more cases of penile cancer being diagnosed (the incidence is increasing), mortality (or …

Molecular research in penile cancer—lessons learned from the past and bright horizons of the future?

C Protzel, PE Spiess - International Journal of Molecular Sciences, 2013 - mdpi.com
Penile cancer is a rare tumor. There is a limited understanding of the biological mediators of
prognostic and therapeutic importance in penile cancer. However, there exists some …

Insights into the management of penile squamous cell carcinoma: from conventional approaches to emerging novel therapies

H Safa, C Mercinelli, PE Spiess, A Necchi… - Expert Opinion on …, 2024 - Taylor & Francis
Introduction Penile squamous cell carcinoma (PSCC), a rare genitourinary cancer, is
associated with poor outcomes due to limited treatment effectiveness, especially in …

The Evolving Landscape of Viral, Immune, and Molecular Biomarkers in Penile Cancer

A Yu, J Chahoud, A Necchi, PE Spiess - Urologic Clinics, 2023 - urologic.theclinics.com
Penile cancer is relatively rare in North America and Europe (< 1% of all malignant
neoplasms); however, it remains a significant health concern with a higher propensity of …

[图书][B] Penile Carcinoma: Therapeutic Principles and Advances

PE Spiess, A Necchi - 2021 - books.google.com
This book provides a comprehensive and state-of the-art approach to caring for penile
carcinoma patients and provides foundational information related to the molecular pathways …