Fibrillar aggregates and soluble oligomers of both Amyloid-β peptides (Aβs) and
hyperphosphorylated Tau proteins (p-Tau-es), as well as a chronic neuroinflammation are …

The inflammatory process has a fundamental role in the pathogenesis of Alzheimer's
disease (AD). Recent studies indicate that inflammation is not merely a bystander in …

It is generally assumed that the neuropathology of sporadic (late-onset or nonfamilial)
Alzheimer's disease (AD) is driven by the overproduction and spreading of first Amyloid-βx …

Long-term evidence has confirmed the involvement of an inflammatory component in
neurodegenerative disorders including Alzheimer's disease (AD). This view is supported, in …

Although the calcium-sensing receptor (CaSR) is expressed by all types of nerve cells in
widespread areas of the human central nervous system (CNS), so far its roles in brain …

Alzheimer's disease (AD) is a neurodegenerative disorder mainly characterized by amyloid-
β (Aβ) plaques, neurofibrillary tangles, loss of synapses and neurons and chronic …

Alzheimer's disease (AD), particularly its sporadic or late-onset form (SAD/LOAD), is the
most prevalent (96–98% of cases) neurodegenerative dementia in aged people. AD's …

Alzheimer's disease (AD) is the most common human neurodegenerative ailment, the most
prevalent (> 95%) late-onset type of which has a still uncertain etiology. The progressive …

Abstract Alzheimer's disease (AD), the most common form of dementia, is characterized by
the accumulation of amyloid β (Aβ) and hyperphosphorylated tau protein aggregates …

Alzheimer's disease (AD) is the most common neurodegenerative disorder, which is
clinically associated with a global cognitive decline and progressive loss of memory and …