Background Atrial fibrillation is self-perpetuating, suggesting that the tachyarrhythmia
causes electrophysiological changes that contribute to the progressive nature of the …

Left atrial (LA) structural and functional remodeling reflects a spectrum of pathophysiological
changes that have occurred in response to specific stressors. These changes include …

Atrial fibrillation occurs and maintains itself in the context of a morphologically and
functionally altered atrial substrate that can be induced by stressors such as underlying …

Cell communication, an essential component of integrated physiological function in
multicellular organisms, is mediated largely through informational molecules, such as …

Current evidence suggests that the pathogenesis of atrial fibrillation (AF) is multifactorial.
The observation that AF, once present, alters the electrophysiologic properties of the atrial …

Atrial fibrillation (AF) is the most prevalent cardiac arrhythmia, affecting 1% to 2% of the
general population. It is characterized by rapid and disorganized atrial activation leading to …

Of all known arrhythmia's, atrial fibrillation (AF) is the most often met in the clinical setting
and it is associated with an increase in mortality risk. Several risk factors for AF have been …

Atrial fibrillation (AF), the most common sustained cardiac arrhythmia encountered in clinical
practice, is associated with increased morbidity and mortality. Electrophysiologically, it is …

Atrial fibrillation (AF), the most common sustained arrhythmia associated with substantial
cardiovascular morbidity and mortality with stroke being the most critical complication. Most …

Chronic atrial fibrillation (AF) is a complex disease with underlying changes in
electrophysiology, calcium signaling and the structure of atrial myocytes. How these …