A series of new quinoline derivatives was designed, synthesized and evaluated for their
antiproliferative activity. The results demonstrated that compounds 11p, 11s, 11v, 11x and …

Quinoline and its analogues are found in various natural products, many of which are active
pharmacophores with significant bioactivities. This article discussed the plethora of …

A series of new quinoline derivatives was designed, synthesized and evaluated as potential
antitumor agents. The results indicated that most compounds exhibited potent …

Background: Along with the progress in medicine and therapies, the exploitation of anti-
cancer agents focused more on the vital signaling pathways and key biological …

Background: On account of significant biological activities, quinoline derivatives have drawn
more attention to the synthesis and biological activities in the search for new therapeutic …

Tetrahydroquinoline and isoquinoline scaffolds are important class of heterocyclic
compounds, which is implied for the development of new drugs and diagnostic for …

Background: The quinoline scaffold has been an attraction due to its pharmacological
activities such as anti-HIV, anti-neoplastic, anti-asthmatic, anti-tuberculotic, anti-fungal, and …

Quinoline heterocycles have been considered important structures due to their diverse
applications in organic synthesis, coordination chemistry, as well as in the fields of drug …

Synthesis and in vitro antiproliferative activities of quinoline derivatives - ScienceDirect Skip
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Several derivatives with a quinoline scaffold and a flexible, semi-flexible or rigid side chains
at position 8 of the quinoline ring were synthesized and assessed for their in vitro activity …