Could intranasal oxytocin be used to enhance relationships? Research imperatives, clinical policy, and ethical considerations

OA Wudarczyk, BD Earp, A Guastella… - Current opinion in …, 2013 - journals.lww.com
Building upon animal-model, human preclinical, and clinical findings, we outline a proposal
for the use of oxytocin in the therapeutic neuroenhancement of contemporary romantic …

Are we there yet? The clinical potential of intranasal oxytocin in psychiatry

J CJ Liu, RA McErlean… - Current Psychiatry Reviews, 2012 - ingentaconnect.com
The hormone oxytocin plays a major role in relationship formation and social functioning in
animals and humans. We review theory and research examining the potential for intra-nasal …

Dramatic improvement in sexual function induced by intranasal oxytocin

K MacDonald, D Feifel - The journal of sexual medicine, 2012 - academic.oup.com
Introduction A variety of sources indicate that oxytocin has beneficial effects on several
components of sexuality. This is a case report on a male who had significant, broad …

[HTML][HTML] Sex, receptors, and attachment: a review of individual factors influencing response to oxytocin

KS MacDonald - Frontiers in neuroscience, 2013 - frontiersin.org
As discussed in the larger review in this special issue (MacDonald and Feifel), intranasal
oxytocin (OT) is demonstrating a growing potential as a therapeutic agent in psychiatry …

Intranasal oxytocin increases positive communication and reduces cortisol levels during couple conflict

B Ditzen, M Schaer, B Gabriel, G Bodenmann… - Biological …, 2009 - Elsevier
BACKGROUND: In nonhuman mammals, the neuropeptide oxytocin has repeatedly been
shown to increase social approach behavior and pair bonding. In particular, central nervous …

Oxytocin effects on the human brain: findings, questions, and future directions

O Weisman, R Feldman - Biological Psychiatry, 2013 - biologicalpsychiatryjournal.com
Since the discovery that intranasal administration of neuro-peptides can have a direct impact
on the human brain, extant research has been devoted to understanding the effects of …

[HTML][HTML] Advances in the field of intranasal oxytocin research: lessons learned and future directions for clinical research

DS Quintana, A Lischke, S Grace, D Scheele… - Molecular …, 2021 - nature.com
Reports on the modulatory role of the neuropeptide oxytocin on social cognition and
behavior have steadily increased over the last two decades, stimulating considerable …

The peptide that binds: a systematic review of oxytocin and its prosocial effects in humans

K MacDonald, TM MacDonald - Harvard review of psychiatry, 2010 - journals.lww.com
Oxytocin is a neuropeptide involved in a wide variety of social behaviors in diverse species.
Recent research on its effects in humans has generated an arresting picture of its role in the …

Overview of human oxytocin research

KM Kendrick, AJ Guastella, B Becker - Behavioral pharmacology of …, 2018 - Springer
Social dysfunction is a core symptom of many psychiatric disorders and current medications
have little or no remedial effects on this. Following on from extensive studies on animal …

The role of oxytocin in parenting and as augmentative pharmacotherapy: critical issues and bold conjectures

MH van IJzendoorn… - Journal of …, 2016 - Wiley Online Library
Despite the sometimes heated debate about the validity of human oxytocin studies,
experimental oxytocin research with intranasal administration is a growing field with …