Although most pituitary tumors are benign, some are invasive or aggressive. In the absence
of specific markers of malignancy, only tumors with metastases are considered malignant …

Abstract Context and Objective: Predicting pituitary tumor behavior remains a challenge.
This multiparameter investigation aimed to identify markers for recurrence and progression …

Abstract According to the World Health Organization classification of pituitary tumors, only
tumors with systemic metastasis must be considered as carcinomas. Invasive tumors with …

Prolactinoma is the most common pituitary tumour in adults. Macroprolactinomas,
particularly in men, may occasionally exhibit a very aggressive clinical course as evidenced …

The molecular pathogenesis of prolactinomas has resisted elucidation; with the exception of
a RAS mutation in a single aggressive prolactinoma, no mutational changes have been …

Integrative genomics approaches associating DNA structure and transcriptomic analysis
should allow the identification of cascades of events relating to tumor aggressiveness. While …

Very few of the genes that are important in pituitary tumor initiation, progression, and
metastasis have been identified to date. To identify potential genes that may be important in …

Recent studies have reported the prevalence of pituitary tumors to be~ 1/1000 population.
Many are prolactin-producing tumors that are managed medically, however, the …

Pituitary tumours are common intracranial neoplasms that cause significant morbidity
through mass effects and/or the inappropriate secretion of pituitary hormones. Despite a …

Pituitary tumours, the most frequent intracranial tumour, are historically considered benign.
However, various pieces of clinical evidence and recent advances in pathological and …