The imbalance of immune response plays a crucial role in the development of diseases,
including glioblastoma. It is essential to comprehend how the innate immune system detects …

Oncolytic virotherapy is a promising immunotherapy approach for cancer treatment that
utilizes viruses to preferentially infect and eliminate cancer cells while stimulating the …

Immune system gene regulation perturbation has been found to be a major cause of the
development of various types of cancer. Numbers of mechanisms contribute to gene …

Currently, there is a lack of effective therapies for the majority of glioblastomas (GBMs), the
most common and malignant primary brain tumor. While immunotherapies have shown …

The innate immune sensing pathways play critical roles in the defense against pathogen
infection, but their roles in cancer immunosurveillance and cancer therapies are less …

RNA sensors detect foreign and endogenous RNAs to protect the host by initiating innate
and adaptive immune response. In tumor microenvironment (TME), activation of RNA …

In recent years, it became apparent that cancers either associated with viral infections or
aberrantly expressing endogenous retroviral elements (EREs) are more immunogenic …

Background: Nucleic acid sensing is an essential strategy employed by the innate immune
system to detect both pathogen-derived nucleic acids and self-DNA released by host …

Gliomas are considered one of the most malignant cancers in the body. Despite current
therapies, including surgery, chemotherapy, and radiotherapy, these tumors usually recur …

The innate immune pathway is receiving increasing attention in cancer therapy. This
pathway is ubiquitous across various cell types, not only in innate immune cells but also in …