Studies of the neurobiological predisposition to consume alcohol (ethanol) and to transition
to uncontrolled drinking behavior (alcoholism), as well as studies of the effects of alcohol on …

The concept of moderate consumption of ethanol (beverage alcohol) has evolved over time
from considering this level of intake to be nonintoxicating and noninjurious, to …

An understanding of the nature and progression of alcohol addiction has emerged:
alcoholism as the result of an imbalance in the brain's natural production of …

Excessive consumption of beverage alcohol (ethanol) is a major health concern worldwide.
Understanding the mechanisms by which ethanol affects neural functioning, after both acute …

The brain is one of the major target organs of alcohol actions. Alcohol abuse can lead to
alterations in brain structure and functions and, in some cases, to neurodegeneration …

Alcohol abuse and alcoholism are the greatest substance abuse problems in the United
States today and contribute to numerous medical and social problems. To deal with many of …

Recent advances in neuroscience have made it possible to investigate the pathophysiology
of alcoholism at a cellular and molecular level. Evidence indicates that ethanol affects …

Ethanol can be viewed as a receptor modulator, selectively altering neurochemical
processes in discrete regions of the CNS. The actions of ethanol at two inotropic receptor …

Page 1 The Biology of Alcoholism Volume 1: Biochemistry Edited by Benjamin Kissin and
Henri Begleiter Page 2 THE BIOLOGY OF ALCOHOLISM Volume 1: Biochemistry Page 3 THE …

Publisher Summary This chapter reviews the physiological actions of alcohol in the nervous
system and discusses the possible cellular and molecular basis of alcohol's behavioral …