Human antigen R (HuR) is an essential regulator of RNA metabolism, but its function in
metabolism remains unclear. This study identifies HuR as a major repressor during …

Human antigen R (HuR) is a member of the Hu family of RNA-binding proteins and is
involved in many physiological processes. Obesity, as a worldwide healthcare problem, has …

The obesity epidemic represents a critical public health issue worldwide, as it is a vital risk
factor for many diseases, including type 2 diabetes (T2D) and cardiovascular disease …

Adipogenesis is a complex and precisely orchestrated process mediated by a network of
adipogenic regulatory factors. Several studies have highlighted the relevance of lncRNAs in …

Brown adipose tissue (BAT) dissipates chemical energy as heat and can counteract obesity.
Micro RNA s are emerging as key regulators in development and disease. Combining micro …

Although expression of the mammalian RNA-binding protein HuD was considered to be
restricted to neurons, we report that HuD is present in pancreatic β cells, where its levels are …

How body size is determined is a long-standing question in biology, yet its regulatory
mechanisms remain largely unknown. Here, we find that a conserved microRNA miR-8 and …

The pleiotropic function of long noncoding RNAs is well recognized, but their direct role in
governing metabolic homeostasis is less understood. Here, we describe a human adipocyte …

In this study, we explored the roles of microRNAs in adipocyte differentiation and
metabolism. We first knocked down Argonaute2 (Ago2), a key enzyme in the processing of …

Adiponectin receptor 1 (AdipoR1) mediates adiponectin's pleiotropic effects in muscle and
liver and plays an important role in the regulation of insulin resistance and diabetes. Here …