Conserved role of Drosophila melanogaster FoxP in motor coordination and courtship song

KJ Lawton, TL Wassmer, DL Deitcher - Behavioural brain research, 2014 - Elsevier
FoxP2 is a highly conserved vertebrate transcription factor known for its importance in
human speech and language production. Disruption of FoxP2 in several vertebrate models …

Conserved regulation of neurodevelopmental processes and behavior by FoxP in Drosophila

A Castells-Nobau, I Eidhof, M Fenckova… - PLoS …, 2019 - journals.plos.org
FOXP proteins form a subfamily of evolutionarily conserved transcription factors involved in
the development and functioning of several tissues, including the central nervous system. In …

A humanized version of Foxp2 does not affect ultrasonic vocalization in adult mice

K Hammerschmidt, C Schreiweis… - Genes, Brain and …, 2015 - Wiley Online Library
The transcription factor FOXP2 has been linked to severe speech and language
impairments in humans. An analysis of the evolution of the FOXP2 gene has identified two …

Knockout of Foxp2 disrupts vocal development in mice

GA Castellucci, MJ McGinley, DA McCormick - Scientific reports, 2016 - nature.com
The FOXP2 gene is important for the development of proper speech motor control in
humans. However, the role of the gene in general vocal behavior in other mammals …

Foxp2 regulates anatomical features that may be relevant for vocal behaviors and bipedal locomotion

S Xu, P Liu, Y Chen, Y Chen… - Proceedings of the …, 2018 - National Acad Sciences
Fundamental human traits, such as language and bipedalism, are associated with a range
of anatomical adaptations in craniofacial shaping and skeletal remodeling. However, it is …

Parallel FoxP1 and FoxP2 expression in songbird and human brain predicts functional interaction

I Teramitsu, LC Kudo, SE London… - Journal of …, 2004 - Soc Neuroscience
Humans and songbirds are two of the rare animal groups that modify their innate
vocalizations. The identification of FOXP2 as the monogenetic locus of a human speech …

Altered social behavior in mice carrying a cortical Foxp2 deletion

VP Medvedeva, MA Rieger, B Vieth… - Human molecular …, 2019 - academic.oup.com
Genetic disruptions of the forkhead box transcription factor FOXP2 in humans cause an
autosomal-dominant speech and language disorder. While FOXP2 expression pattern are …

FoxP2 regulation during undirected singing in adult songbirds

I Teramitsu, SA White - Journal of Neuroscience, 2006 - Soc Neuroscience
Learned vocal communication, including human speech, is a socially influenced behavior
limited to certain animals. This ability requires auditory feedback during vocalization, which …

Differential coexpression of FoxP1, FoxP2, and FoxP4 in the Zebra Finch (Taeniopygia guttata) song system

E Mendoza, K Tokarev, DN Düring… - Journal of …, 2015 - Wiley Online Library
Heterozygous disruptions of the Forkhead transcription factor FoxP2 impair acquisition of
speech and language. Experimental downregulation in brain region Area X of the avian …

The structure of innate vocalizations in Foxp2‐deficient mouse pups

S Gaub, M Groszer, SE Fisher… - Genes, Brain and …, 2010 - Wiley Online Library
Heterozygous mutations of the human FOXP2 gene are implicated in a severe speech and
language disorder. Aetiological mutations of murine Foxp2 yield abnormal synaptic plasticity …