Per-and post-remote ischemic conditioning attenuates ischemic brain injury via inhibition of the TLR4/MyD88 signaling pathway in aged rats

J Lv, W Yan, J Zhou, H Pei, R Zhao - Experimental Brain Research, 2021 - Springer
Remote ischemic conditioning (RIC), as an emerging protective method, might be used
clinically to prevent ischemia–reperfusion injury (IRI) in ischemic stroke. In this study, we aim …

Non-invasive remote limb ischemic postconditioning protects rats against focal cerebral ischemia by upregulating STAT3 and reducing apoptosis

Z Cheng, L Li, X Mo, L Zhang… - International …, 2014 - spandidos-publications.com
The signal transducer and activator of transcription 3 (STAT3) signaling pathway has been
implicated in cell apoptosis and inflammatory processes. Ischemic preconditioning (IPC) and …

Limb remote postconditioning alleviates cerebral reperfusion injury through reactive oxygen species-mediated inhibition of delta protein kinase C in rats

Q Wang, X Zhang, Q Ding, B Hu, Y Xie, X Li… - Anesthesia & …, 2011 - journals.lww.com
BACKGROUND: Remote ischemic postconditioning (RPostC) is an emerging concept for
cerebral infarction protection, and its potential protective mechanisms have not been well …

Acute remote ischemic preconditioning alleviates free radical injury and inflammatory response in cerebral ischemia/reperfusion rats

XL Meng, DL Zhang, SH Sui - Experimental and …, 2019 - spandidos-publications.com
Remote ischemic preconditioning (IPreC) is an effective strategy to defend against cerebral
ischemia/reperfusion (IR) injury; however, its mechanisms remain to be elucidated. The aim …

Remote ischemic conditioning reduced cerebral ischemic injury by modulating inflammatory responses and ERK activity in type 2 diabetic mice

C Liu, J Yang, C Zhang, X Geng, H Zhao - Neurochemistry International, 2020 - Elsevier
Remote ischemic preconditioning (RIPreC) and postconditioning (RIPostC) have been
demonstrated to attenuate brain injury after ischemic stroke in healthy animals. This study …

[HTML][HTML] Remote ischemic conditioning attenuates oxidative stress and inflammation via the Nrf2/HO-1 pathway in MCAO mice

YY Sun, HJ Zhu, RY Zhao, SY Zhou, MQ Wang, Y Yang… - Redox biology, 2023 - Elsevier
The protective effects of remote ischemic conditioning (RIC) on acute ischemic stroke have
been reported. However, the protective mechanisms of RIC have not been fully elucidated …

Remote limb ischemic postconditioning protects against cerebral ischemia-reperfusion injury by activating AMPK-dependent autophagy

H Guo, L Zhao, B Wang, X Li, H Bai, H Liu, L Yue… - Brain research …, 2018 - Elsevier
Remote limb ischemic postconditioning (RIPoC) is a promising adjunct treatment for
cerebral ischemia-reperfusion (IR) injury. However, the underlying mechanisms have not …

Limb remote ischemic postconditioning protects cerebral ischemia from injury associated with expression of HIF-1α in rats

Y Zong, L Jiang, M Zhang, F Zhou, W Qi, S Li, H Yang… - BMC neuroscience, 2015 - Springer
Background Limb remote ischemic postconditioning (LRIP) can ameliorate cerebral
ischemia–reperfusion injury (IRI), while the underlying mechanism remains elusive. Hypoxia …

Remote limb ischemic postconditioning promotes motor function recovery in a rat model of ischemic stroke via the up‐regulation of endogenous tissue kallikrein

D Liang, XB He, Z Wang, C Li, BY Gao… - CNS neuroscience & …, 2018 - Wiley Online Library
Aims Remote ischemic conditionings, such as pre‐and per‐conditioning, are known to
provide cardioprotection in animal models of ischemia. However, little is known about the …

Effects of different remote ischemia perconditioning methods on cerebral infarct volume and neurological impairment in rats

S Otsuka, Y Itashiki, A Tani, T Matsuoka, S Takada… - Scientific reports, 2023 - nature.com
Remote ischemic perconditioning (RIPerC) is a novel neuroprotective method against
cerebral infarction that has shown efficacy in animal studies but has not been consistently …