Ischemic postconditioning has been demonstrated to alleviate brain ischemia/reperfusion-
induced neuronal apoptosis; however, the protective mechanisms underlying the improved …

Background Remote limb ischemic postconditioning (RLIPoC) has been demonstrated to
protect against ischemic stroke. However, the underlying mechanisms of RLIPoC mediating …

We recently demonstrated that limb remote preconditioning (LRP) protects against focal
ischemia measured 2 days post-stroke. Here, we studied whether LRP provides long-term …

Limb remote ischaemic postconditioning (RIP ostC) is an effective and well‐acknowledged
treatment for brain ischaemia injury. The present study aimed to evaluate the role of fibulin‐5 …

Attenuation of ischemic injury can be achieved by priming the brain with a sub-lethal
ischemic insult, a phenomenon known as ischemic preconditioning (IP). We sought to …

Remote ischemic preconditioning (RIPC) is an intriguing approach which exposes a remote
organ/tissue to a non-lethal transient ischemia/reperfusion (I/R) in order to potentiate the …

Highlights•LPostC up-regulated the SIRT1 and PGC-1α protein expressions in ischemic
cortical tissue.•SIRT1/PGC-1α signaling pathway inhibition increased cerebral infarction …

The treatment of reperfusion injury requires measures beyond timely reperfusion.
Conventional postconditioning (PostC) of ischemic tissues offers a strategy to reduce …

Integrity of the blood-brain barrier structure is essential for maintaining the internal
environment of the brain. Development of cerebral infarction and brain edema is strongly …

Ischemic preconditioning (IPC) has been demonstrated to provide a neuroprotection against
brain damage produced by focal cerebral ischemia. However, it is elusive whether ischemic …