Local circuit allowing hypothalamic control of hippocampal area CA2 activity and consequences for CA1
V Robert, L Therreau, V Chevaleyre, E Lepicard… - Elife, 2021 - elifesciences.org
The hippocampus is critical for memory formation. The hypothalamic supramammillary
nucleus (SuM) sends long-range projections to hippocampal area CA2. While the SuM-CA2 …
nucleus (SuM) sends long-range projections to hippocampal area CA2. While the SuM-CA2 …
Hypothalamic supramammillary control of cognition and motivation
AJ Kesner, M Mozaffarilegha, KT Rajamani… - Journal of …, 2023 - Soc Neuroscience
The supramammillary nucleus (SuM) is a small region in the ventromedial posterior
hypothalamus. The SuM has been relatively understudied with much of the prior focus being …
hypothalamus. The SuM has been relatively understudied with much of the prior focus being …
REM sleep-active hypothalamic neurons may contribute to hippocampal social-memory consolidation
The hippocampal CA2 region plays a key role in social memory. The encoding of such
memory involves afferent activity from the hypothalamic supramammillary nucleus (SuM) to …
memory involves afferent activity from the hypothalamic supramammillary nucleus (SuM) to …
Supramammillary nucleus afferents to the dentate gyrus co-release glutamate and GABA and potentiate granule cell output
Y Hashimotodani, F Karube, Y Yanagawa, F Fujiyama… - Cell reports, 2018 - cell.com
The supramammillary nucleus (SuM) of the hypothalamus projects to the dentate gyrus (DG)
and the CA2 region of the hippocampus. Although the SuM-to-hippocampus circuits have …
and the CA2 region of the hippocampus. Although the SuM-to-hippocampus circuits have …
Memory circuits: CA2
RA Piskorowski, V Chevaleyre - Current opinion in neurobiology, 2018 - Elsevier
The hippocampus is a central region in the coding of spatial, temporal and episodic memory.
Recent discoveries have revealed surprising and complex roles of the small area CA2 in …
Recent discoveries have revealed surprising and complex roles of the small area CA2 in …
Hypothalamic glutamate/GABA cotransmission modulates hippocampal circuits and supports long-term potentiation
MI Ajibola, JW Wu, WI Abdulmajeed… - Journal of …, 2021 - Soc Neuroscience
Subcortical input engages in cortico-hippocampal information processing. Neurons of the
hypothalamic supramammillary nucleus (SuM) innervate the dentate gyrus (DG) by …
hypothalamic supramammillary nucleus (SuM) innervate the dentate gyrus (DG) by …
Hippocampal CA1 circuitry dynamically gates direct cortical inputs preferentially at theta frequencies
CW Ang, GC Carlson, DA Coulter - Journal of Neuroscience, 2005 - Soc Neuroscience
Hippocampal CA1 pyramidal neurons receive intrahippocampal and extrahipppocampal
inputs during theta cycle, whose relative timing and magnitude regulate the probability of …
inputs during theta cycle, whose relative timing and magnitude regulate the probability of …
Separable actions of acetylcholine and noradrenaline on neuronal ensemble formation in hippocampal CA3 circuits
In the hippocampus, episodic memories are thought to be encoded by the formation of
ensembles of synaptically coupled CA3 pyramidal cells driven by sparse but powerful mossy …
ensembles of synaptically coupled CA3 pyramidal cells driven by sparse but powerful mossy …
CA2: A highly connected intrahippocampal relay
SJ Middleton, TJ McHugh - Annual Review of Neuroscience, 2020 - annualreviews.org
Although Lorente de No'recognized the anatomical distinction of the hippocampal Cornu
Ammonis (CA) 2 region, it had, until recently, been assigned no unique function. Its location …
Ammonis (CA) 2 region, it had, until recently, been assigned no unique function. Its location …
Chronic loss of CA2 transmission leads to hippocampal hyperexcitability
Hippocampal CA2 pyramidal cells project into both the neighboring CA1 and CA3 subfields,
leaving them well positioned to influence network physiology and information processing for …
leaving them well positioned to influence network physiology and information processing for …