Current reconstructive approaches to large craniofacial skeletal defects are often
complicated and challenging. Critical-sized defects are unable to heal via natural …

Over the past decades, there has been a substantial amount of innovation and research into
tissue engineering and regenerative approaches for the craniofacial region. This highly …

Conditions such as congenital anomalies, cancers, and trauma can all result in devastating
deficits of bone in the craniofacial skeleton. This can lead to significant alteration in function …

Craniofacial fractures and bony defects are common causes of morbidity and contribute to
increasing health care costs. Successful regeneration of bone requires the concomitant …

Oral Diseases (2010) 16, 709–716 Although advances in surgical techniques and bone
grafting have significantly improved the functional and cosmetic restoration of craniofacial …

Engineering craniofacial bone tissues is challenging due to their complex structures. Current
standard autografts and allografts have many drawbacks for craniofacial bone tissue …

Autogenous bone grafting remains a gold standard for the reconstruction critical‐sized bone
defects in the craniomaxillofacial region. Nevertheless, this graft procedure has several …

Regeneration of normal shape, architecture, and function of craniofacial tissues following
congenital abnormality, trauma, or surgical treatment presents special problems to tissue …

The primary goals of craniofacial reconstruction include the restoration of the form, function,
and facial esthetics, and in the case of pediatric patients, respect for craniofacial growth. The …

Facial deformities require precise reconstruction of the appearance and function of the
original tissue. The current standard of care—the use of bone harvested from another region …