Treating oxidative stress in heart failure: past, present and future
A van der Pol, WH van Gilst, AA Voors… - European Journal of …, 2019 - Wiley Online Library
Advances in cardiovascular research have identified oxidative stress as an important
pathophysiological pathway in the development and progression of heart failure. Oxidative …
pathophysiological pathway in the development and progression of heart failure. Oxidative …
Oxidative stress and inflammation in the evolution of heart failure: from pathophysiology to therapeutic strategies
A Aimo, V Castiglione, C Borrelli… - European journal of …, 2020 - journals.sagepub.com
Both oxidative stress and inflammation are enhanced in chronic heart failure. Dysfunction of
cardiac mitochondria is a hallmark of heart failure and a leading cause of oxidative stress …
cardiac mitochondria is a hallmark of heart failure and a leading cause of oxidative stress …
Oxidative stress and redox signalling in cardiac hypertrophy and heart failure
M Seddon, YH Looi, AM Shah - Heart, 2007 - heart.bmj.com
Substantial evidence suggests the involvement of oxidative stress in the pathophysiology of
congestive heart failure and its antecedent conditions such as cardiac hypertrophy and …
congestive heart failure and its antecedent conditions such as cardiac hypertrophy and …
Redox signaling in heart failure and therapeutic implications
D Weissman, C Maack - Free Radical Biology and Medicine, 2021 - Elsevier
Heart failure is a growing health burden worldwide characterized by alterations in excitation-
contraction coupling, cardiac energetic deficit and oxidative stress. While current treatments …
contraction coupling, cardiac energetic deficit and oxidative stress. While current treatments …
Oxidative stress in heart failure: what are we missing?
DB Sawyer - The American journal of the medical sciences, 2011 - Elsevier
Over the past several decades, investigations in humans and animal models of heart failure
(HF) have provided substantial evidence that oxidative stress is increased in HF and …
(HF) have provided substantial evidence that oxidative stress is increased in HF and …
Oxidative stress and heart failure.
Despite advances in treatment, chronic congestive heart failure carries a poor prognosis and
remains a leading cause of cardiovascular death. Accumulating evidence suggests that …
remains a leading cause of cardiovascular death. Accumulating evidence suggests that …
Oxidative stress and heart failure
H Tsutsui, S Kinugawa… - American journal of …, 2011 - journals.physiology.org
Oxidative stress, defined as an excess production of reactive oxygen species (ROS) relative
to antioxidant defense, has been shown to play an important role in the pathophysiology of …
to antioxidant defense, has been shown to play an important role in the pathophysiology of …
Pathophysiological role of oxidative stress in systolic and diastolic heart failure and its therapeutic implications
Systolic and diastolic myocardial dysfunction has been demonstrated to be associated with
an activation of the circulating and local renin–angiotensin–aldosterone system (RAAS), and …
an activation of the circulating and local renin–angiotensin–aldosterone system (RAAS), and …
Novel aspects of ROS signalling in heart failure
AD Hafstad, AA Nabeebaccus, AM Shah - Basic research in cardiology, 2013 - Springer
Heart failure and many of the conditions that predispose to heart failure are associated with
oxidative stress. This is considered to be important in the pathophysiology of the condition …
oxidative stress. This is considered to be important in the pathophysiology of the condition …
Oxidative stress in heart failure: more than just damage
DJ Grieve, AM Shah - European heart journal, 2003 - academic.oup.com
Chronic heart failure (CHF) continues to cause substantial morbidity and mortality despite
major therapeutic advances, such as the use of angiotensin-converting enzyme (ACE) …
major therapeutic advances, such as the use of angiotensin-converting enzyme (ACE) …
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