Rationale: Dopamine D 2 receptors are postulated to play an important role in modulating
the reinforcing effects of abused drugs including ethanol. Objectives: This experiment …

Dopamine D3 receptors have been implicated in the behavioral effects of abused drugs
including ethanol. The present experiments characterized the acquisition of ethanol-induced …

Pharmacological blockade studies have supported a role of the dopamine system in ethanol
reward for many years, but receptor subtype specificity has been difficult to establish …

Rationale Novelty associated with behavioral testing has been shown to enhance
psychostimulant-and morphine-induced locomotor stimulation. Evidence has demonstrated …

Considerable evidence suggests that the mesolimbic dopaminergic system is an important
substrate for the rewarding effects of ethanol consumption. Previous data have …

Rationale We previously reported that mice lacking dopamine D3 receptors (D3R) were
resistant to behavioural sensitization to ethanol (EtOH). Since knockout mice have …

Abstract The effects of SDZ-205,152, a synthetic mixed D1/D2 dopamine receptor agonist,
was investigated in rats trained to orally self-administer ethanol (10% w/v) in a free-choice …

Separate lines of evidence suggest that neuroadaptations associated with ethanol (EtOH)
reinforcement can be initiated by chronic EtOH preexposure and a signaling pathway …

The present study examined the effects of the acute intraperitoneal (ip) administration of the
selective dopamine (DA) D3 receptor antagonist SB‐277011A (10, 20 or 30 mg/kg ip) on the …

Although dopaminergic transmission has been strongly implicated in alcohol self-
administration, the involvement of specific dopamine receptor subtypes has not been well …