Obesity, a global epidemic of the modern era, is a risk factor for cardiovascular diseases
(CVD) and diabetes. The pervasiveness of obesity and overweight in both developed as …

Obesity is a multifactorial disorder that results in excessive accumulation of adipose tissue.
Although obesity is caused by alterations in the energy consumption/expenditure balance …

Obesity and related metabolic diseases are currently a threat to global public health. The
occurrence and development of these conditions result from the combined effects of multiple …

The human GI tract harbors a diverse and dynamic microbial community comprising
bacteria, archaea, viruses and eukaryotic microbes, which varies in composition from …

The distal gut harbours microbial communities that outnumber our own eukaryotic cells. The
contribution of the gut microbiota to the development of several diseases (eg obesity, type 2 …

The current obesity epidemic clearly has many causes, including the impact of our modern
world on both our diet and our lifestyle/physical activity. Although many interventions have …

There is mounting evidence that microbiome composition is intimately and dynamically
connected with host energy balance and metabolism. The gut microbiome is emerging as a …

Large-scale alterations of the gut microbiota and its microbiome (gene content) are
associated with obesity and are responsive to weight loss. Gut microbes can impact host …

The gut microbiome has been proposed to play a causal role in obesity. Here, we review the
historical context for this hypothesis, highlight recent key findings, and critically discuss …

The aetiology of obesity has been attributed to several factors (environmental, dietary,
lifestyle, host, and genetic factors); however none of these fully explain the increase in the …