Mutants of Shigella flexneri defective in aerobactin-mediated iron transport were assayed for
virulence in several model systems. A Tn5 insertion mutant was invasive in HeLa cells …

ABSTRACT In Shigella boydii 0-1392, genes encoding the synthesis and transport of the
hydroxamate siderophore aerobactin are located within a 21-kb iron transport island …

The sit-encoded iron transport system is present within pathogenicity islands in all Shigella
spp. and some pathogenic Escherichia coli strains. The islands contain numerous insertion …

Genes encoding the synthesis and transport of aerobactin, a hydroxamate siderophore
associated with increased virulence of enteric bacteria, were mapped within a pathogenicity …

Shigella spp. have transport systems for both ferric and ferrous iron. The iron can be taken
up as free iron or complexed to a variety of carriers. All Shigella species have both the Feo …

Shigella species are able to grow in a variety of environments, including intracellularly in
host epithelial cells. Shigella have a number of different iron transport systems that …

Shigella flexneri possesses multiple iron acquisition systems, including proteins involved in
the synthesis and uptake of siderophores and the Feo system for ferrous iron utilization. We …

Iron limitation, a condition encountered within mammalian hosts, induces the synthesis of a
number of proteins in pathogenic Shigella species. These include several outer membrane …

The iron uptake systems of Plesiomonas shigelloides strains were determined. Siderophore
production was not detected by chemical or biological assays, and the strains tested were …

To assess the importance of TonB-dependent iron transport systems to growth of Shigella in
vivo, a tonB mutant of Shigella dysenteriae was isolated and tested in cultured cells. The …